Ultimate Scholar

Li Mu's question stunned everyone present.

What's the meaning?

Is the composition they determined not complete enough?

What really plays a role is another ingredient hidden inside?

They couldn't help but wondered.

"Boss, why...why do you say that?" Kingsley Weir wondered.

"Just answer whether you have measured all the ingredients first." Li Mu did not rush to explain.

Kingsley Weir thought for a moment, and then said: "If you only talk about the ingredients that have not been determined... there may indeed be some ingredients that have not been fully determined. After all, I believe the boss also knows that for this kind of ingredients extracted from nature. When it comes out, there's always going to be some natural ingredients that we don't fully discover, especially if it's in really small amounts."

Li Mu nodded slightly, and said directly: "So, the next task is to find these undiscovered trace ingredients."

"And I can be sure that what we are looking for now lies in these unknown ingredients."

Speaking of the draft paper Li Mu found from the side, he wrote down the labels of several sets of experiments on it. After finishing writing, he handed it directly to Kingsley Weir.

"Just repeat these sets of experiments and measure the ingredients of the liquid medicine. If my analysis is correct, the content of this unknown ingredient in these sets of experiments is relatively higher, and it should be easier to find .”

Kingsley Weir quickly took the paper, looked at it for a long time, and finally asked carefully: "Among the sets of experiments you wrote, I found that the effects of two sets of experiments are not good. , and it has not even reached the average level, are you sure that the content of that unknown ingredient is higher in the medicinal liquids of these two groups of experiments?"

Isn't the better the effect, the more ingredients it contains?

Kingsley Weir was quite clear about this, at least in this tiny case.

However, Li Mu just shook his head and said, "If you study traditional Chinese medicine, you should also know the properties of medicine. Different combinations of medicines will produce different effects."

"Of course, this is just the experience handed down from Chinese medicine, but if it is reflected in chemistry, it means that different components will inhibit each other."

"It's like a catalyst, and an inhibitor."

"I mean you should understand?"

"Oh, maybe it can help you find that unknown ingredient..."

After thinking about it, Li Mu took the piece of paper from Kingsley Weir again, and wrote a chemical formula on it again.

【C9H7NO2NH3...】

Then, based on this chemical formula, he drew its molecular structure.

In organic chemistry, the chemical formulas of organic molecules may be the same, but once the structures are different, the effects will be completely different.

Just like that sentence, structure determines function.

"Basically, if there is no wrong guess, it is this thing that affects the display of the effect of the unknown ingredient."

Kingsley Weldon was surprised when he saw this ingredient.

"This is... 8-hydroxy-2-aminoquinoline?"

Because he also noticed the abnormal performance of this component in the experiment, it sometimes appears, sometimes it does not, and it seems to be irregular.

At first, Kingsley Weir thought it was the effect of this thing, but after experiments, this thing was useless at all, and it even seemed to affect the effect of thrombolysis.

But now that Li Mu brought it up separately, and explained that it might be the "culprit" that suppressed the effect of the unknown ingredient, he immediately realized this possibility!

His face was full of deep surprise.

Of course, the faces of his former students around him were also full of surprise.

After a few words from Li Mu, they all thought of this point as if enlightened.

Looking at the molecular structure diagram drawn on the piece of paper in his hand, Kingsley Weir finally decided after a long time of thinking that this was the key to their ultimate success!

Taking a deep breath, he looked at Li Mu: "Is this also what you found from the data analysis?"

Li Mu nodded slightly.

"This...can I ask how it was done?" Kingsley Weir said a little embarrassedly: "I really want to learn."

Li Mu's scientific and systematic analysis method is much superior to his method of looking at a lot of experimental data and relying on intuition to find the salient points!

Relying on intuition to search, sometimes you can only catch the blind, but with Li Mu's analysis, you can find clues from the clues!

For Kingsley Weir, this method was simply too greedy.

But Li Mu frowned, and asked, "Are you sure you want to study?"

"I'm sure!" Kingsley Weir nodded repeatedly.

Of course, the assistants around also nodded repeatedly.

Just kidding, they were stunned by the huge amount of data for several days, but it didn't take long for Li Mu to get started, and he discovered something that they hadn't discovered before without even calculating it.

Are these Thai pants spicy?

Seeing their anticipation, Li Mu smiled, and finally said: "Okay, then I will demonstrate it to you."

Naturally, it is impossible to have a blackboard for them to use in the GMP laboratory, so Li Mu directly took the paper and pen, and started to calculate on the table.

And Kingsley Weir and others gathered around him and watched.

"It may be a little difficult, so don't worry too much."

Before starting to write, Li Mu also made a special reminder.

Kingsley Weir said with a good feeling about himself: "It's not particularly difficult, anyway, I have studied for a while these days, so I should be able to understand it... I can still get an A+ in my undergraduate mathematics course. "

Regarding his words, Li Mu just smiled without making any comments.

"Really? That's good."

Then, his demo began.

Then, there were several more confused faces in the laboratory.

Kingsley Weir silently looked at the mathematical formulas written by Li Mu.

"...?"

Obviously everyone has learned general knowledge, why is Li Mu able to use it so well?

From then on, he deeply understood one point, that is, when Li Mu said it was a bit difficult, they had to pay attention, because it would definitely be very, very difficult for them. \b

...

In the end, Li Mu gave them a complete demonstration of his own analysis process.

Although Kingsley Weir and they all ended up watching it with a dazed face. \b

They also finally understood why in the past few months, the entire biomedical community has been discussing Li Mu's data analysis method very heatedly, but not many people have produced any results.

Learn math first!

"Well, I thought I'd figured something out, but now it looks like..."

Kingsley Weir sighed helplessly. \b

Not a class at all.

Li Mu smiled.

In fact, he hasn't said that this seemingly complicated process is very simple to him.

Just like at the beginning, he only needs to use the computer in his mind to process the data, and he will get the result soon.

Of course, there is no need to say such things, so as not to affect the mentality of Kingsley Weir and the others.

Putting away the pen in his hand, he stood up and said, "I will put this analysis process here, and you can study it by yourself."

"Next, it's up to your experiments."

Kingsley Weir recovered from the shock just now, then stood still and said, "Regarding this point, please rest assured, since we have such a detailed analysis, we will definitely be able to succeed."

"Do you think so?"

He looked at his former students and current assistants, and asked with a smile.

"yes!"

These students all nodded.

For their experiments, the biggest worry is not knowing what to do next.

The experiment can only be repeated continuously, with the intention of finding phenomena that have not been discovered.

This is also one of the reasons why the large number of biological papers published in "Science", "Nature", and "Cell" cannot be reproduced by others.

Excluding the possibility of data falsification, the only remaining possibility is that they themselves have repeated many times when doing experiments, and it will of course become more difficult for others to reproduce.

But now, with Li Mu's analysis to help them pinpoint the target and scope, it will naturally be of great help to their research.

This is why the biological community has always been so enthusiastic about Li Mu's data analysis method.

So, next, their experiment officially started.

The first thing is to reconfigure the liquid medicines used in the experiments marked by Li Mu, such as how many grams of Rehmannia glutinosa juice to take, or the extracts that have been tormented, and then make the ratio.

It looks like alchemy - in fact, what they do is really similar to alchemy.

The unknown ingredient is the gold they want to refine.

For the research of drug experiments, the most important thing is to find the effective ingredients for the symptoms, and then extract the active ingredients and mix them with other auxiliary ingredients to make drugs.

So generally speaking, a medicine may weigh 0.5 grams, but the main ingredients that really work are often only a few tenths of a milligram, and the remaining components are generally diluents, adhesives, and colorants. And so on, such as flavoring agents, that is, ingredients that make the originally bitter medicine taste sweeter.

Of course, no matter how those active ingredients are used to make money.

This time the experiment will probably take a while. For those who study biology, it is normal to live directly in the laboratory.

Of course, as the boss, Li Mu could have left the lab directly, but with a certain interest in the experiments, he stayed and decided to watch their experiments for a few more days.

In this way, time passed quickly.

...