Since 1981 Health School

  Section 409 Minimum Standards of Sponsorship

  De Nelson went back to discuss with several technicians for a long time, and then asked another question:

   "Doctor Lan, how did you know about our company's new drug omeprazole? In addition, you can be sure that you can help us prove the bactericidal effect of omeprazole in clinical trials?"

  Chen Qi interjected at this time:

"The principle of omeprazole is actually not complicated. We have seen it in related papers. It is mainly able to pass proton pump inhibitors, and can specifically inhibit the secretory microtubules formed by the apical membrane of B cells and the hydrogen ions in the bubble plasma. It can effectively inhibit gastric acid secretion.

But to inhibit gastric acid secretion, the mainstream in the market is not omeprazole, but Ranitidine (ranitidine) and cimetidine (cimetidine), I think this is your trouble, how to compete with these two drugs for the market .

   Similarly, our worry is that clinical experiments require a lot of funds and drugs. Everyone knows that our country has just reformed and opened up, and the funds allocated to our technicians are not so sufficient, which will affect the experimental process.

  So my wife and I came here with only one purpose, that is, win-win cooperation. The two sides jointly set up a research group. You are responsible for providing funds and drugs, and we are responsible for clinical research. For the results, we only require the authorship of the paper, and the research results can be owned by you Aslila. "

  No way, medical research, especially clinical treatment plans, cannot be patented.

   Otherwise, there will be a quadruple therapy or triple therapy, then Chen Qilan and Lijuan can become a rich man with this patent.

  So besides funding, what Chen Qi wanted to fight for was the right to reputation.

  He is not the Holy Mother, but he has never thought of working for capitalists for free. If they have income, of course the husband and wife should also have income.

  In addition, as long as this project is first settled in Yuezhong People's Hospital, it will be extremely beneficial to both the hospital and Lan Lijuan's own career development.

   This can give Lan Lijuan a certain voice in the international or domestic medical circle, which is a higher starting point than ordinary doctors.

  After she grows up, she will have a certain status in the hospital. When she becomes an "infectious disease doctor", she will let the flow take its course and win more favorable conditions.

  The seniority ranking in China is too powerful. If she wants to be the director of the infectious disease department or become an expert in infectious diseases, Lan Lijuan can only find another way to save the country.

  As soon as Denilson heard about the two antacids ranitidine and cimetidine, he knew that these two Chinese doctors had obviously come prepared.

   This is to tell him, if you do not choose to cooperate with us, we will go to "Glaxo" or "SmithKline" to discuss cooperation.

  Anyway, acid-suppressing drugs are not unique to your company Asrila, not to mention that you are still a second-rate company, far from being called a pharmaceutical giant.

   Talk to smart people, some things don't need to be said too thoroughly.

  In fact, this is Chen Qi fooling these stupid Swedish foreigners.

  What Chairman Denilson didn’t know was that in a few decades, two drugs, ranitidine and cimetidine, would be detected to contain the carcinogenic N-nitrosodimethylamine.

   This is a harmful substance with very strong liver toxicity and can cause cancer in the human body. It can be quickly absorbed through the respiratory tract and digestive tract to damage the human liver.

  In the list of carcinogens published by the World Health Organization, NDMA belongs to Class 2A carcinogens.

  The curative drug became a harmful drug, so ranitidine and cimetidine quickly began to withdraw from the gastric drug market.

   In contrast, proton pump inhibitors are emerging.

   Rabeprazole, omeprazole, pantoprazole, lansoprazole, esomeprazole, etc., are surging one by one, quickly occupying half of the stomach medicine.

   It has become a veritable cornucopia, and money is earned.

   But Asrila Pharmaceuticals doesn’t know about it. Their omeprazole is still new, and they never realized that they could dominate the world in the future.

  After listening to the suggestions of Chen Qi and Lan Lijuan, Denilson decided to hold a closed-door meeting internally to discuss whether to "sponsor" this topic.

  Chen Qi took the opportunity to call Professor Segel outside.

  In the small garden, Chen Qi looked around and saw that there was no one around, so he went straight to the point and asked:

   "Professor Segel, do you think our subject has a future? Can it be applied clinically?"

  Segel nodded firmly:

   "In principle, I think your subject is the real pathogenic principle of gastrointestinal diseases. You and your wife have discovered a very remarkable subject, which can definitely win the Nobel Prize."

  Nordic men are all straight men of steel.

  Chen Qi smiled: "Then Professor, would you like to join our research group?"

  Professor Segel was shocked when he heard that:

   "Chen, this, this is not appropriate, your subject is already very deep, and you don't need help from others at all. If I join, I don't think I may be able to help."

   "No, you can help us, our research group also needs you. Firstly, you are a famous gastroenterologist, and stomach disease is your specialty. We all share the same goal."

   (Voice-over: Chen Qi, are you a gastroenterologist?)

"Secondly, my wife and I, and our mentors are all doctors from Huaguo, lacking international influence and lack of influence on Alalila's decision-making. If you join our research group, you will definitely bring benefits to Aslila. confidence.

  You also know that our project funds are very tight, so we need money, the more the better, and we also need some advanced equipment, which all need money, and now we need Aslila to pay for it. "

   Chen Qi’s words are very straightforward. From the perspective of Chinese people, it should be very inappropriate. This kind of money is too much money. How did you learn socialism values?

   But from the perspective of a foreigner, this is normal. Asrila’s new drug project is not of a public welfare nature, and his pharmaceutical company is planning to make a lot of money.

  So supporting doctors to conduct clinical trials is equivalent to advertising for pharmaceutical companies in disguise, and it is very natural to get a reasonable remuneration for their new drug platform.

   Otherwise, where do those top doctors get the money to live in the mansion on the top of the mountain, drive in a free car, and go in and out of the first class?

  Professor Segel understood Chen Qi's intention as soon as he heard it, which made him ecstatic.

   After all, it is not too difficult for the most famous gastroenterologist in Sweden to negotiate with Aslila on behalf of Doctor Hua and ask for more money.

  Similarly, although Sweden is a small country, the most famous Nobel Prize is in Sweden.

  The Nobel Prize in Biology or Medicine is assessed by the Karolinska Institutet in Stockholm, and he himself is a professor at the Karolinska Institutet, which also has a certain influence.

  As soon as he thought of joining the Helicobacter pylori research team, he could personally research a revolutionary medical invention that would create an era, Professor Segel couldn't help being excited.

  What if one day he might also win a Nobel Prize?

   "Chen, your suggestion is very good. I am willing to accept your invitation and join your team. Don't worry, if you need help, just tell me, and the negotiation work with Aslila will be on my shoulders.

   And I can assure you, I won't ask for a penny. I am not short of money. What I lack is a great research project. You have given me all of this. This is really great news. I can't wait to go to Huaguo. "

   Chen Qi was also happy when he saw that the Swedish doctor was so upbeat.

  The hands of the two were tightly held together, which represented that Professor Segel had officially boarded the ship.

  After a long time, I don’t know how Professor Segel lobbied, Chairman Denilson finally made a decision to sponsor the Helicobacter pylori research group with his new drug omeprazole.

  However, there are differences within the company as to how much to sponsor.

  When the capitalists give money, they need to see a return, and every copper coin must be heard.

   People are not fools, you say that people trust you 100% on a topic?

   "Dr. Chen, Dr. Lan, since Professor Segel has joined your research group, and he has repeatedly assured us the significance of this research and the decisive factor for the promotion of our new drug omeprazole, so we decided to sponsor your research.

  But we can’t invest too much money until we see concrete results. I hope you can understand, so we decided to temporarily sponsor you according to the lowest European standards. Of course, don’t worry, as long as there are results, we will increase follow-up sponsorship. "

  Chen Qi and Lan Lijuan were a little disappointed when they heard it. After talking for a long time, they only sponsor according to the minimum standard. How much money can they get?

   What the two of them thought more about was that in 1982, Chen Qi gave Lan Lijuan 2,000 yuan to start the Helicobacter pylori project at her own expense.

  Since people say it is the minimum standard, it is estimated that it is only a few hundred thousand or two hundred thousand. This amount of money is also a huge sum of money to others, but to Chen Qi it is just the labor fee for a few flying knife surgeries.

   But no matter how small a fly’s legs are, they are still meat. If you don’t take them for nothing, at least they will cover all the clinical medicine, which is also a big expense.

   Moreover, Chen Qi knew that in order to obtain the best clinical effect, ranitidine could not, but omeprazole, that is, omeprazole!

  Chairman Denilson continued a little embarrassedly:

"So we can only sponsor you with a maximum of 2 million U.S. dollars, and ask you to come up with results within 3 years. Ahem, although the money is small, you can rest assured. I assure you that as long as the project is successful, our new drug can be fully promoted. In the international market, we will give you no less than 2 million US dollars in rewards, and the rewards are for you personally."

  Professor Segel was a little dissatisfied when he heard it, and muttered in his mouth: "2 million, too little."

  Chen Qi and Lan Lijuan were shocked when they heard this, are they there? $2 million? Do you Europeans have any misconceptions about minimum standards?

  (end of this chapter)