my life simulator
Page 381
This is the immune mechanism at work.The symptoms of fever are the normal mechanism of the immune system to deal with the invasion of viruses.
And then... the immune system is still going crazy!
Even if T cells do not "call friendly forces", the army of T cells will still cause a violent immune response in the human body, and a "factor storm" will still occur.
It's just...it seems that the scale is not that serious.
Lu Li hurriedly concocted a drug to control the madness of the immune system and maintain the vital signs of the experimental body.
Cardiac injections, adrenal hormones, first aid, and various emergency measures were used one after another. I don't know how long it took before this experimental human body finally stabilized.
"Sure enough, my thinking is right!"
Lu Li let out a long breath and grinned, "Removing the ability of T cells to call allies can reduce the chance of the immune system going crazy."
Although this little bit of progress cannot make a key breakthrough in CAR-T cancer treatment technology, but...as a postgraduate thesis, the gold content is definitely enough.
After closing the virtual laboratory, Lu Li opened his eyes, another night passed.
After getting up and washing up, he went out to have breakfast, and when Lu Li returned home, he sat in front of the computer and started writing his thesis.
"CAR-T technology, a preliminary study on the mechanism of shielding T cell information transmission!"
Lu Li sat in front of the computer desk, clacking and typing on the keyboard with his hands. A paper with detailed data, clear experimental procedures, and authenticity was easily written.
One Chinese, one English, all done.
Then, Lu Li called Professor He, "Teacher, my research topic has been..."
"Already think about the subject? It's quite efficient!"
Before Lu Li could finish speaking, Professor He took over the conversation, "Okay, you can send me the project! I'll report it to you."
"That... is not a project, but a thesis. I wrote a thesis."
Lu Li quickly explained: "Teacher, I wrote a paper and sent it to your email. Please correct it!"
"paper?"
Professor He was stunned for a moment. You didn't even choose a topic, so you wrote a thesis?Is it the kind of water-filled paper with a mixed name?
"I'll take a look!"
Professor He didn't say much, and was going to read it before talking.If it's really flooding the papers, then Lu Li should be dealt with properly and kill this evil trend.
Sitting back at his desk, Professor He turned on his computer, and saw the thesis sent by Lu Li in his mailbox.
After clicking on the paper, Professor He was taken aback when he saw the title "CAR-T Technology, A Preliminary Study on the Mechanism of Blocking T Cell Information Transmission".
CAR-T technology?This is still a cutting-edge scientific research project in the world!
Mechanism of screen T cell information dissemination?New gene editing technology?
Professor He suddenly looked serious, and quickly looked at it seriously.
The paper was in duplicate, one in Chinese and the other in English. Professor He didn't bother to read the English version, so he picked up the Chinese version and read it.
There is no water in the whole paper, it is all dry goods.
In the paper, Lu Li described the new gene editing direction of T cells in detail, every step was clear, and the experimental data was also very detailed.
Judging from the paper, as long as Lu Li's experimental procedures are followed, the gene editing technology that shields the T cell information transmission mechanism is completely repeatable.
From a theoretical analysis, shielding the information transmission mechanism of T cells can indeed effectively reduce the "factor storm" and reduce the chance of the immune system going crazy.
"This kid... so quietly, he actually set off a thunderbolt on me!"
A bright smile appeared on Professor He's face, "A breakthrough in CAR-T technology, this is a major scientific research achievement! Not bad! Not bad!"
After reading the paper, Professor He quickly downloaded the paper and printed it out.Then, Professor He picked up the paper materials, turned around and ran out.
All the way to the Tumor Research Office of Fudan Medical College, I found Professor Guo who is engaged in the research of tumor medical technology.
"Old Guo, Lao Guo, take a look at this paper."
While shouting, Professor He pointed at Professor Guo the information in his hand.
"paper?"
Professor Guo from the Tumor Research Office looked up at Professor He, "Old He, you are so excited, does this paper have something to offer?"
"It's not just in stock?"
When he came to Professor Guo, Professor He handed over the paper, "Look for yourself!"
"CAR-T technology, a preliminary study on the mechanism of shielding T cell information transmission? The author... Lu Li?"
Seeing the title and the author, Professor Guo immediately became serious, "So it was written by Lu Li. This kid actually researched this? It's amazing!"
Picking up the paper, Professor Guo sat down and read it seriously.
After reading it over and over again, Professor Guo had a look of surprise on his face, "From the perspective of the experimental procedures and ideas, this brand-new direction of gene editing has...successful?"
"It looks so!"
Professor He grinned, "I came to you just to repeat this experiment."
"Row!"
Professor Guo got up quickly, "I also want to verify it. If the experiment can be repeated, then... that would be great!"
It is astonishing that a postgraduate student actually came up with such a high-quality thesis and made such a breakthrough in a cutting-edge scientific research project.
So, with an order, Professor Guo summoned all the master's and doctoral students in the oncology laboratory, handed out a paper to them, and asked them to repeat Lu Li's experiment.
"Lu Li's thesis? CAR-T technology?"
Seeing this paper, the doctoral students and master students in the laboratory were all stunned.
This fellow Lu Li has just been a graduate student for less than a year, right?This is the result of such scientific research?
Originally, Lu Li's previous "asking" made Professor Guo full of praise for Lu Li, which made everyone feel embarrassed.
Now... how the hell did you actually produce results?
Does this keep people alive?
He secretly slandered that these "research dogs" could only follow Professor Guo's instructions and repeat Lu Li's experiments.
Everyone acted immediately, like an assembly line, constantly preparing cut proteins and transcriptases, and continuously injecting them into T cells.
Compared with Lu Li doing all the steps by himself, the current assembly line mode is much more efficient.
After an hour, more than 300 samples of T cell gene modification have been prepared in the laboratory.
Among more than 300 specimens, four T cells that accurately shielded the information transmission mechanism appeared.
The experiment was a success!
"Hahahaha! It really worked!"
Professor He couldn't help laughing out loud, "Lu Li really has achieved results! Hahahaha!"
The surrounding graduate students and doctoral students were all buried in silence.
Professor Guo looked at the successfully prepared T cells, then at Professor He who was grinning from ear to ear, and let out a deep sigh in his heart.
How did such an excellent student fall into Lao He's hands?What a shit luck!
Afterwards, Professor He sent Lu Li's paper to the core journal "Chinese Medicine", and attached Fudan University's repeated experiment records.
After receiving this submission, the editorial department of "Chinese Medicine" magazine was shocked when it saw the title, and then saw the repeated experiment records of Fudan University attached at the back, and immediately passed it to the reviewers without saying a word .
Fudan University has already verified it once, and this is clearly a scientific research result that has been tested in practice.
There are several reviewers, some are professors of medicine at Yenching University, and some are academicians of the Chinese Academy of Sciences.
After receiving the manuscript, the reviewers read it carefully.
After reading Lu Li's paper, and seeing Fudan University's repeated experiment records, the reviewers were amazed again.
The author is a graduate student?
A master's student actually came up with such a scientific research result?
How powerful is Fudan's scientific research?
With a sigh, the reviewer arranged for another repeat experiment.The result... proved once again that Lu Li's thesis is absolutely correct.
Not long after, the "Chinese Medicine" magazine officially published Lu Li's paper.
Once the paper came out, it caused a huge shock in the scientific community, and also caused a huge repercussion in the society.
"Conquering cancer is no longer a dream. Chinese scientist Lu Li has made a major breakthrough in CAR-T anti-cancer technology!"
Lu Li: Is this a major breakthrough?
Chapter 356 Come and see, my son is a scientist
The so-called "significant breakthrough", Lu Li is a little bit disapproving.
Even if the information transmission mechanism of T cells is blocked and the ability of T cells to call friendly forces is limited, the immune response is still very violent.
Treatments with stronger side effects than therapeutic effects are undoubtedly unsuccessful.
But... all the anti-cancer methods so far have had more side effects than the treatment effect.
Commonly used radiation therapy, while radiation kills cancer cells, it kills more normal cells, and radiation is also carcinogenic, almost like drinking poison to quench thirst.
Chemotherapy is more severe!It is completely killing one thousand enemies and three thousand self-damages.
As for the cutting-edge CAR-T technology, the lethal effect is far greater than the therapeutic effect.
However... even if the side effects are so huge, there are still countless people chasing after them, scrambling to get treatment.
Being terminally ill and watching life go by day by day, such fear makes people completely indifferent to any side effects, even if there is only one ten thousandth, or even one hundred thousandth hope, they still have to try.
Therefore, Lu Li actually underestimated his scientific achievements.
……
Milliken.
In the ward of a private hospital, an old gentleman was lying on a hospital bed, and a doctor in a white coat stood beside him.
"Doctor Henry, are you here today to tell me that there is no hope?"
On the old face, a pair of cloudy eyes revealed a deep unwillingness.
"No! On the contrary, sir!"
A smile appeared on Dr. Henry's face, "I have brought you hope!"
"hope?"
There was a gleam in the old man's eyes, "This is the best news I've heard recently! So... where is my hope?"
"CAR-T technology!"
Dr. Henry replied: "Sir, a few days ago, a Chinese scientist named Lu Li improved the CAR-T technology, which can greatly reduce the factor storm caused by the immune response. So... your hope has appeared!"
"Thank God!"
The old man stretched out his hand and made a sign of the cross on his chest.
"You should thank this Chinese scientist, Lu Li!"
Doctor Henry thought to himself: God didn't save you, but...Lu Li's research results may save you!
"Yes! Thank you Lu Li!"
There was a gleam of hope in the old man's eyes.
……
The same scene is happening in many places around the world.
Lu Li's improved CAR-T technology, the gene editing technology that shields the T cell information transmission mechanism, has brought a glimmer of hope to countless people who are in despair.
This new technology, which is still very immature, can't even be said to be successful, won't save everyone's life.
Only those with weaker immune responses, or those with stronger physical fitness and able to withstand the immune response, will gain life.
However... For people in despair, this little hope is the motivation for them to persevere.
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