Auto chess in the operating room

Chapter 315 Becoming the Leader of Provincial Subject Points
Tang Lou went straight to the diagnosis:

[Patient: Guo Caier, female, 30 years old

Symptoms: Allergy to swollen lips
Diagnosis: Yida syndrome, lip edema caused by crayfish allergy. 】

Tang Lou glanced at Guo Cai'er's lips speechlessly, it was exactly the same as when Zhang Yida was allergic to crayfish, and said happily: "Don't worry, I checked your symptoms, it should be crayfish allergy , nothing serious."

After hearing what Tanglou said, Guo Caier realized that he had called a lot of crayfish last night in a daze. Fortunately, fortunately.

After all, the affairs of Tang Lou and Cheng Sisi are well known to everyone in the general surgery department, how could she, Guo Caier, do such a thing, although she doesn't really mind to pick and choose for Tang Lou...

"Then I'll go first."

Tang Lou confirmed that nothing happened last night, heaved a sigh of relief, and escaped from Guo Cai'er's room as if fleeing, and must stay away from Guo Cai'er in the future.

Looking at the Tang Lou who fled in a hurry, Guo Caier didn't know whether it was peace of mind or regret after knowing that the two of them were safe and sound, touched his sausage mouth: "Hiss, it hurts me to death."

Tang Lou called Didi, hurried back to his dormitory, washed up, and then rushed to the first hospital of the city.

However, what he didn't expect was that when he walked into the gate of the First Hospital of the City, he saw a long banner that read: "Congratulations on the establishment of a provincial key discipline in the field of acute abdomen in the General Surgery Department of the First Hospital of the City. success."

"The key subjects are down?"

Tanglou was surprised and happy. This was something that Director Cheng had been looking forward to before, but he didn't expect to confirm it before he went to Zijingang Medical College for further studies.

[Ding, help the General Surgery Department of the First Hospital of the city to successfully establish a provincial key discipline, task reward: storage bar +10]

After reading this, Tanglou's heart skipped a beat. This was really a big deal. Speaking of which, he had clearly felt that there were not enough storage slots recently. The addition of 10 storage slots really solved a big problem.

Tanglou thought for a while and instead of going to the cardiovascular department, he went directly to Cheng Jian's office in the general surgery department to express his congratulations.

After knocking on the door, after Tang Lou entered, the director, deputy director, and attending physicians of the general surgery department were all in Cheng Jian's office.

Everyone was celebrating, and everyone was overjoyed when they saw Tang Lou.

"Tang Lou, you are here. This time our department was able to successfully set up a provincial-level subject point, and you have contributed a lot."

Seeing Tang Lou, Qingping hurried over to say hello, his eyes full of approval and appreciation.

"Yes, Doctor Tang, this time it really depends on you. In addition to your improved new opening technique, this time the president, vice president and directors of the Provincial Medical Association unanimously approved the approval of our city's first hospital. The establishment of key disciplines. Among them, the recommendations and proposals of Professor Liu Pingguo, Professor Wen Dalong, and Director Chen Qilong directly set the tone of the entire conference."

"Professor Liu said that in the construction of key disciplines in the First City Hospital, in addition to the newly developed procedures, the potential of our department, the most important thing is that they are unanimously optimistic about you!"

Hangcui Mountain was also very excited and said that no one expected that Tang Lou would have such an influence in the Provincial Medical Association.

"Tang Lou, Director Cheng and Director Shen discussed together just now, and they are planning to recommend you as the leader of the key discipline of general surgery in the First City Hospital. Of course, all of this will be officially appointed after you return from Zijingang Hospital."

Yan Ruoyun also said very seriously.

Tang Lou was also very surprised when he heard some big bosses in the general surgery department say this. He actually became the leader of the key discipline this time?
"Director Cheng, Director Shen, I'm afraid this is inappropriate. After all, my qualifications are too young, and I'm afraid I can't take on this important task."

After thinking about it, Tang Lou was ready to decline. After all, no matter which department he is in, the academic leader is the most respected doctor. After all, he is too young.

"Tang Lou, don't be humble. With your academic achievements and future potential, besides you, who else in the department would dare to be the leader of this subject? If you can't do it, who can do it? Tang Lou, this matter, That’s it, I’ve already reported to Dean Yang, and Dean Yang also meant the same thing. When you come back from Zijingang Hospital this time, you will directly appoint the deputy chief physician.”

Cheng Jian made the final decision.

Director Shen at the side also agrees very much. In fact, this matter has been discussed in the upper management of the hospital. Originally, the hospital wanted to take it easy, but knowing that Tang Lou became a doctoral student of Professor Liu Juzi, he boarded the For the special issue of "Huaxia Cardiovascular Diseases Journal", there is no hospital that does not want to try its best to keep a promising doctor and scientific research talent like Tang Lou.

The leader of the general surgery department is undoubtedly the most suitable, and Tang Lou has the most affection.

Now the appointment of Tanglou's academic leader and the deputy director after returning from advanced studies is to stabilize Tanglou.

"Tang Lou, if you don't accept it, Director Cheng won't worry about sending you to Zijingang Hospital for further study."

Qingping said with a stern face on the side.

"Okay, Director Cheng, don't worry, all doctors, I will definitely go back to the City No. [-] Hospital after I finish my advanced studies. After all, Hecheng is my root."

Hearing what Tang Lou said, all the doctors were very satisfied.

Originally, Tang Lou went to Zijingang Hospital for further study and had to learn the process. Since it was published in the special issue of "Chinese Journal of Cardiovascular Diseases" and with the help of Professors Liu Juzi and Liu Pingguo, Tang Lou's trip to Hangzhou was directly on the agenda.

And Tang Lou also had a preliminary idea about the subjects under Liu Juzi's school when he went to Zijingang Hospital in the future.

He is going to study the direction of research and development of new drugs, and his main research field is antihypertensive drug CCB preparations.

Under the one-star anti-hypertensive drug CCB research and development technique (one-star, 3), Tanglou also has a general understanding of the research and development of new drugs.

The process from R&D to marketing of conventional new drugs is a very complicated process, and the capital investment involved is also very staggering. Moreover, a lot of manpower and material resources are often invested, and few drugs can be successfully marketed in the end.

It can be said that the whole process is generally divided into the following stages:
A, the first is basic research.This process is to start with patients, clinical pathology, and statistical data to find and verify potential targets.

B, Pharmacology and biomarker development.Including pharmacology and druggability studies of targets, biomarker studies related to targets and prognosis.

C, Lead compound discovery.Lead compounds are compounds with certain biological activity obtained through various ways and means, and are usually obtained by in vitro screening for further structural modification and optimization.

D, lead compound optimization, preclinical candidate compound confirmation, preclinical research to support declaration, production and quality control (CMC).In this link, potential drug candidate molecules are screened out, systematic pharmacodynamic studies and toxicology studies are carried out, and samples used to support clinical research need to be produced under the conditions of quality management (GMP).

E, Clinical research.It mainly conducts clinical trials, including Phase I, Phase II, and Phase III clinical trials.Each phase has a different goal and a different scale.

F. Regulatory Approval.The main goal of this stage is to register and file the drug for marketing.The United States applies to the FDA, the European approval authority is EMA, and China applies to the National Medical Products Administration (CNDA).

G, Postmarketing surveillance.It is mainly to monitor all information related to drugs after marketing, including effectiveness, safety, ethnic differences, non-standard use, etc.

H, Medical Landscape.Including competition situation, pricing strategy, market share, doctor education, etc.These determine the commercial success of the drug.

It is a costly process for a drug to be developed from the source to Phase 3 clinical trials.The world's pharmaceutical giants have calculated that an average new drug costs hundreds of millions of dollars.

Drug research and development is an industry with high investment and high risk accompanied by high return.Once the drug is successfully marketed, the rewards are also amazing.

There is a term in the industry called "blockbuster", which refers to a drug with annual sales of more than $10 billion.An extreme example is Pfizer's patent-protected lipid-lowering drug Lipitor, whose global sales in 2010 were US$101.33 billion.

It is foreseeable that as long as Tang Lou's antihypertensive drug CCB is successfully developed and approved for marketing, it will definitely be such a blockbuster drug!

Now, under the R&D technology of antihypertensive drug CCB, Tang Lou has solved the basic research in the early stage, the discovery of lead compounds and the confirmation of preclinical candidate compounds. What he has to do is to start with animal experiments and form complete experimental data. Human experiments will then be carried out step by step.

And these are the main purposes for Tang Lou to go to Professor Liu's school this time!
(End of this chapter)