Doctor's Life Simulator

Chapter 364 Simulation!Detailed side effects of Pfizer smoking cessation pills
Looking at this award, Qin Lang was also a little overjoyed, it turned out to be a research project with the potential of the Nobel Prize in Medicine.

The Nobel Prize in Physiology or Medicine, one of the five Nobel Prizes established in accordance with Nobel's will, aims to honor those who have made important discoveries or inventions in the fields of physiology or medicine.

Since the Nobel Prize in Physiology or Medicine was awarded for the first time in 1901, only in 1935, Wu Lien-teh, a pioneer of modern medicine in Huaguo, became the first Chinese nominated for the award. It was not until 2015 that Tu Youyou won the first Nobel Prize in Physiology in Huaguo. or a medical award.

The winner of the Nobel Prize is often announced in October every year. The award ceremony is held in Stockholm, Sweden on December 10, the anniversary of Nobel's death, and the award is presented by the King of Sweden in person.

This award is generally considered the highest honor that can be achieved in the field of physiology or medicine!
Once he can win the Nobel Prize, he will undoubtedly go down in history and become the top leader in the medical field.

Rao is the state of mind simulated by Qin Lang for several generations, and there are huge waves.

Such an opportunity is in front of him, of course Qin Lang will not let it go.

Moreover, through this task, Qin Lang also deduced the real cause of the patient, which seems to have something to do with the side effects of Pfizer's smoking cessation drug.

Qin Lang lifted his spirits, and suggested to Director Zhu and Director Qing:

"Director Zhu, Director Qing, I have an immature suggestion. Maybe the patient really had a myocardial infarction as Director Qing judged, but he is not a common ST-segment elevation myocardial infarction."

Hearing Qin Lang's words, Director Qing and Director Zhu on the side were a little surprised, especially Director Zhu, who now attaches great importance to Qin Lang's suggestion, and immediately asked: "Director Qin, tell me more specifically?"

Regarding Director Zhu's attitude, Director Qing also looked at this young man. Could it be that he really has a unique opinion?

Qin Lang explained unhurriedly:
"It's like this. When I was in the Second Hospital of Harbin Medical University, I exchanged some cases with Professor Liu. I happened to meet similar patients. Conventional coronary angiography is indeed the gold standard for diagnosing coronary heart disease, but there are still some cases. Some special patients are easily missed by simple coronary angiography."

Hearing the experience of Professor Liu from the Second Hospital of Harbin Medical University, Director Zhu and Director Qing both showed serious expressions. In their opinion, Professor Liu from the Second Hospital of Harbin Medical University is a ceiling-level figure in the cardiovascular field. He said that, so he must be right.

The two directors were a little envious for a while. Qin Lang was able to communicate and study with Professor Liu face to face, and the two directors calmed down and analyzed slowly in Qin Lang.

"In daily practice, myocardial infarction is missed. The reason is that the occlusion of the coronary artery in patients with non-ST-segment elevation myocardial infarction is located in the distal end, and the affected myocardial area is limited to the lateral or posterior wall, which is not easy to detect. .”

"The pathogenesis of patients with non-ST-segment elevation myocardial infarction is mainly myocardial oxygen consumption or oxygen supply imbalance. In addition to the increase in cardiac oxygen consumption, it may also be due to plaque rupture or myocardial microcirculation embolism after plaque surface thrombus attachment. , Coronary angiography at this time showed that the blood flow of the epicardial coronary arteries was smooth, so no abnormalities were found in the examination."

Listening to Qin Lang's introduction, the two directors nodded again and again, which was quite rewarding.

Director Qing looked at Qin Lang who was talking eloquently, and he felt a little appreciation in his heart, what a young talent.

Sure enough, the growth of a top doctor, talent, guidance from a famous teacher, and support from noble people are all indispensable.

"So, if Director Qin really judges the patient as non-ST elevation myocardial infarction like you do, how are you going to detect these atypical myocardial infarctions?"
Director Zhu asked very curiously, which was also a brand new knowledge point for him.

Looking at Qin Lang, Director Zhu felt as if he followed his teacher back then.

Qin Lang immediately took out the new assistive technology mastered in the simulated world and shared it with Director Zhu and Director Qing:

"This method is called dynamic electrocardiogram examination, and it is checked with GE Seer Light dynamic electrocardiogram and HOLTER software analysis."

After listening to Qin Lang's introduction, Director Zhu's eyes also brightened. This is really a brand new method.

Director Zhu rubbed his hands together: "Then Director Qin, let's try now."

"it is good!"

Qin Lang immediately took the two directors to start the dynamic electrocardiogram examination. Half an hour later, as Qin Lang speculated, he got the test results. The patient was indeed a very rare and hidden myocardial infarction.

After the diagnosis, Director Zhu and Director Qing immediately felt relieved, they were too experienced in the treatment of myocardial infarction.

Director Zhu treated the patient immediately, including anti-ischemic therapy, antithrombotic therapy, and interventional therapy based on the risk stratification of the patient.

When Director Zhu carried out the treatment step by step, Director Qing also left the ward in admiration. He really admired Qin Lang.

However, what puzzled him was, what was the cause of the myocardial infarction in the patient?

The same problem troubled Director Zhu, but as long as the patient could be brought back from the death line, Director Zhu would be very fortunate.

As for what caused it, he can only ask for a deep understanding.

This kind of situation is very common in clinical practice. Many patients and many diseases have no real cause of disease. The human body is really an overly complicated and mysterious system.

Under Director Zhu's treatment, Xie Fei's condition was finally brought under control.

In the ward, Director Zhu confessed to Xie Fei with a solemn expression:
"Xie Fei, you have to thank Director Qin a lot this time for giving you a dynamic electrocardiogram, otherwise the diagnosis and treatment would have been delayed. What you are suffering from is a very dangerous and atypical myocardial infarction."

Hearing Director Zhu's words, Xie Fei was also afraid for a while. Fortunately, he met Director Qin. However, Xie Fei looked at the young Qin Lang and couldn't believe it. Qin Lang was really too young.

Not enough, Xie Fei also understands that genius cannot be measured by qualifications, so he immediately thanked:

"Director Qin, I really want to thank you this time. The grace of saving lives is like recreating."

Xie Fei was very grateful, but he was also very puzzled, obviously he had already paid attention to rest and maintenance, even quit smoking, why did he suddenly have a myocardial infarction.

Facing Xie Fei's question, Director Zhu could only speak vaguely, but it was all specious speculation.

Director Zhu looked at Qin Lang beside him, and asked with a touch of luck, "Director Qin, what do you think?"

Following Director Zhu's words, Xie Fei also looked at the young Director Qin.

Qin Lang thought for a while, then asked, "Have you made any changes in your living habits recently, and have you taken any medicine?"

Xie Fei hadn't spoken yet, but Director Zhu on the side started talking instead. He had already asked the doctor in detail before:

"Patients, there are indeed some changes in their living habits recently, but they are all positive changes. It is reasonable to say that they are not the cause of the disease."

After Director Zhu said something, Qin Lang grasped the key point:
"Exclude all the impossibilities, then there is only one possibility. The biggest change you have made in these days is to quit smoking and take the smoking cessation drug of Pfizer in the United States. It is very likely that the side effects of this drug exist."

Hearing Qin Langshi's shocking words, Director Zhu also turned pale with shock, and Xie Fei's expression changed while lying on the bed:
"Director Qin, this is impossible. This smoking cessation drug is launched by Pfizer, and it has been certified by the US FDA. I have asked the pharmacy and read the instructions of this drug. There is no such side effect."

Xie Fei couldn't believe it, but there was also a murmur in his heart.

"Director Qin, speaking of which, I've been taking medicine on time these days, and there's still a box of smoking cessation pills in my pocket that I've only taken two."

Xie Fei handed Qin Lang the medicine he had been taking every day from his pocket.

[Ding, the host can consume 1 life simulation point, put the drug into the drug research and development laboratory for testing, and obtain its detailed pharmacokinetics and side effects.Yes, consume a little simulation point for simulation? 】

Of course, Qin Lang chose to simulate. In the simulated world, this job was done by the team of Vice President Gao Jun of Zhejiang Provincial Hospital of Traditional Chinese Medicine.

But this time, with the help of the drug research and development laboratory, Qin Lang himself was able to lead the team to complete the process, which undoubtedly simplified the entire process and provided enough time for himself to fight back against Pfizer.

[Consuming 1 point of life simulation point to simulate Chantix. Obtain Chantix pharmacokinetic data.]

[Pharmacokinetics: Absorption reaches peak plasma concentration 3-4 hours after oral administration.The blood drug concentration can reach a steady state within 4 days, and the absorption of oral administration is not complete, and the systemic bioavailability is not high, so there are some hidden dangers. 】

[Distribution: Chantix is ​​distributed in various tissues including brain tissue, and the steady-state apparent fractional volume is 415 liters (%CV=50)]

【Biotransformation: The metabolic rate is very low, 92% of the original drug is excreted through urine.】

[Adverse drug reaction: It may cause irritability, insomnia, depression, behavior change, agitation, depression, suicidal behavior, and may cause serious mental illness, schizophrenia, bipolar manic depression, severe depression, myocardial infarction Infarction, angina.After taking the drug for seven weeks, the risk of vascular disease is much higher than that of normal people]

[The simulation is complete, do you get the simulation result? 】

Qin Lang originally only got a general understanding of the side effects of the smoking cessation drug through the text information of the simulator, but after the real simulation was completed, it was a little unbelievable.

It can only be said that the side effects of this smoking cessation drug are too great, especially the high probability of increasing the risk of vascular disease.

This is not a smoking cessation drug, it is simply a killer drug.

If it weren't for my own intervention and investigation, I believe that based on the medical profession's rhetoric, I would definitely think that the ex-smoking patients will have psychological abnormalities, depression, excitement, etc. after they stop smoking for a while because they are used to smoking.

No one will think about the problem of smoking cessation medicine itself. As for cardiovascular disease, it is even more difficult to associate it with smoking cessation medicine.

"I really didn't expect that Pfizer Pharmaceuticals in the United States has no bottom line. In order to suppress the Ming's Pharmaceutical Group, it would do something like this."

Through the text description of the simulator, Qin Lang certainly understands that the promoter and leader of this is the person in charge of the Huaguo District and the Zhejiang Province of Pfizer, which he offended before.

Its heart is awkward!

With the simulation information of this drug research and development laboratory, Qin Lang only needs to collect enough case data. After all, the results are already there, and only the skeleton needs to be filled.

Qin Lang took the smoking cessation medicine provided by Xie Fei, and solemnly issued the doctor's order:
"Xie Fei, don't take this smoking cessation drug anymore. I will take this smoking cessation drug to the laboratory for testing. At the same time, I also need your follow-up cooperation. I will use your case information as one of the typical cases. If it is really the problem of Pfizer’s smoking cessation drug, believe me, I will make them pay enough. I will also provide you with enough compensation!”

Hearing Qin Lang's words, Director Zhu on the side looked sideways, even absurd. If it was someone else, he would naturally think it was a little doctor's imagination.

However, it was Qin Lang who said this, and Director Zhu believed this conclusion a little bit. Could it be that it is really a problem with Pfizer's smoking cessation medicine?
Thinking about it, if Qin Lang really came to such a conclusion, it would be a big event that caused an earthquake in the medical circle.

Listening to Qin Lang's instructions, Xie Fei nodded, naturally he did not dare to take this smoking cessation medicine again.

Moreover, if it is really the problem of smoking cessation medicine, as Qin Lang said, he must seek justice!

After exhorting Xie Fei with Director Zhu, Qin Lang also left the ward and contacted Wang Rou's team immediately.

According to the current progress, Qin Lang's self-developed bupropion smoking cessation drug is ready to go.

The team has already invested in the new anti-tumor drug project, and Qin Lang has arbitrarily stuffed a new task, which is the case and data collection of the side effects of Pfizer's new drug, as well as the writing of the paper.

Wang Rou was somewhat dissatisfied with Qin Lang's sudden request, but after all, Qin Lang was the boss, so she could only follow Qin Lang's orders without complaint.

Under the coordination of Qin Lang, each hospital also collected some case materials and information according to Qin Lang's admission requirements, and immediately provided them to Wang Rou's team.

Looking at the case data collected continuously, Wang Rou and others also slowly discovered the possible huge side effects of Pfizer's smoking cessation drug.

Obviously, Wang Rou and the others were also stunned by Qin Lang's big move. Before contacting, Pfizer's Zhejiang Province director Wanfeng's arrogance at the new drug launch conference, and for Qin's pharmaceutical company, Wang Rou The team, Qin Lang's belittling, Wang Rou also felt a burst of excitement.

If Qin Lang's research direction is correct, then this can be said to be a major scandal in Pfizer's long pharmaceutical history, and it will be a big news that has caused a sensation in the pharmaceutical industry.

Dr. Wang Rou was really shocked by her boss.

Research and development of a new smoking cessation drug, disclosure of Pfizer's shocking scandal, no matter which thing is exciting!
While Wang Rou was high-spirited and engaged in research according to Qin Lang's design, Qin Lang was also preparing to go to Ming's Pharmaceutical Group to carry out his commercial layout.

After all, if you want to be rewarded for a research project with a Nobel Prize, you must reach the Forbes Under 30 Elite List, so you can only do a good job.

But think about it, this is all from my own family, and the left pocket goes into the right pocket. Anyway, in the future, Qin's Pharmaceutical Company and Ming's Pharmaceutical Group will be inherited by his and Tang Yue's precious daughters. Thinking about it this way, there is no routine. .

(End of this chapter)