I can extract side effects.

Chapter 5 Working together to accelerate clinical trials

Standing in front of the window, Wei Kang looked at the backs of the three people walking out of the company, the corners of his mouth couldn't help curling up, and he was very happy.

The tacit understanding with Lao Sun is still so strong. Thanks to his assist, a few words have disintegrated the psychological defense of these people. Otherwise, the price of withdrawing shares must not have been so small, and the process would never have been so easy.

Maybe it's because I usually don't care about world affairs and concentrate on studying, which led to the establishment of silly, sweet, stubborn and easy to bully people too successfully.

Although the prices of houses in the suburbs of Haishi have risen, they were priced at the price of cabbage when they were bought back then. Now they can be exchanged for 20% of the company's shares, which is not a loss.

It's just that when the news of the new drug's success spreads in the future, with the personalities of these people, there will definitely be another big scene. This must be guarded against, and some preparations must be made.

He gloated in his heart, but the old grandson next to him was hesitant to speak, it seemed that he had a lot to say, but he didn't know where to start.

In the end, he sighed and said, "Xiaokang, I won't say much about the withdrawal of shares. But about the acquisition, should you think about it again and leave a way out."

There was a tinge of warmth in Wei Kang's heart. Old Sun really cared about him and thought of him.

He wanted to tell Lao Sun the news of the successful development of the new drug, share the joy with him, opened his mouth, and swallowed all the words.

If Lao Sun found out about the success of the drug test, he would not be able to hide the fact that he was suffering from advanced liver cancer. He didn't want to make Lao Sun worry about him anymore.

After thinking about it, he felt that he could reveal some good news for a while, so as to save the old Sun from frowning all day long, so he said seriously: "Uncle Sun, don't worry too much, actually I have some good news to tell you."

"I recently developed an improved anti-cancer drug, which is progressing rapidly, and I estimate that it should be able to produce results soon. After a while, the clinical trials will start, and the company will be brought back to life."

The wrinkles on Lao Sun's face immediately stretched out, like a blooming chrysanthemum, he asked in disbelief: "Xiao Kang, are you comforting me, are you really? That would be great."

Wei Kang nodded: "It's true. But once this incident happens today, don't make a big deal of it for the time being, and wait until the third clinical phase."

Old Sun clapped his hands abruptly and said, "That's right, you're still smart, these old boys will definitely go back on their word if they know the news."

The gaze that looked at Wei Kang also became relieved, and he praised: "Mr. Wei is really mature now, and I haven't seen you for three days, which is impressive."

He immediately murmured: "In this case, clinical trials are the most important thing, and the funds must be squeezed out first. Let's delay the supplier's payment first. We have never defaulted before. This time there is no way. But we are also doing things according to industry practice.”

"There are still a few receivables that have been delayed for a long time. I am on a business trip and put down my face to collect the money. They are all old acquaintances. It should not be a big problem on my face. As for President Zhang, I will visit him in person and talk well. Said, it should be possible to renew the loan, and only pay interest when it expires..."

"Uncle Sun, thank you for your hard work." Wei Kang looked at the old sun's white sideburns, moved in his heart, and nodded heavily: "I will contact Zhang Bo of the CRO, the clinical trial must be accelerated, and we will not be afraid of running out of funds when the results come out gone."

"There is also a need to rectify the internal affairs of the company. In the past, there were too many incompetent bastards stuffed in by the affiliates. We just took this opportunity to lay off employees and let them go, leaving behind the hard-working people."

"Okay, if you have the spirit, of course I support you. I'll make a list for you later."

The two looked at each other and smiled, all the tacit understanding was in silence.

Wei Kang returned to the office, sat on a chair, and called Zhang Bo, the head of the CRO company he had cooperated with for many years.

CRO companies, also known as pharmaceutical R&D contract outsourcing companies, are key links in the pharmaceutical R&D industry chain and play a significant role in shortening the pharmaceutical R&D cycle and reducing R&D costs.In terms of shortening the R&D cycle, for the same R&D project, generally speaking, the time required by CRO companies is about 20% to 30% shorter than the time required by pharmaceutical companies themselves.

In addition, labor costs account for more than one-third of the general cost of new drug R&D, and the salary of R&D personnel in CRO companies is 20% to 30% lower than the average salary of R&D personnel in large pharmaceutical companies. R&D expenses of the firm.

Because the investment in new drug R&D is too large, the success rate is too low, and the R&D cycle is very long, more and more pharmaceutical companies have adopted the CRO model in order to improve efficiency, reduce R&D costs, and control risks. All outsourced.

Among other things, an authoritative data released in 2018 shows that the return on investment in new drug research and development has dropped to 1.9%, a record low.

It can be seen from this that the development of new drugs is really close to death. It is no wonder that most pharmaceutical companies are buying some expired patents to produce generic drugs. Even ambitious pharmaceutical companies will devote their energy to improving drugs and developing new drugs. All of them are fighters who live to death in pharmaceutical companies.

Of course, CRO companies will also help to apply for approval documents, find resources for drug testers, etc., which can be described as a one-stop service.

The company Weikang found is very professional. They have cooperated with each other for many years and have always been very satisfied.

"Mr. Zhang, are you busy? Is it convenient to answer the phone?"

"Haha, it's Mr. Wei, it's convenient, what's going on with you recently? Are there any new drugs that are going to be clinically available?"

"Mr. Zhang, we have a new anti-cancer drug, which is an improved drug. We need to complete the second phase of clinical trials. This needs to be completed as soon as possible, and then continue to do the third phase of clinical trials. Is it okay?"

Zhang Bo was taken aback: "Huh? Anti-cancer drug? Have you really developed it?"

"of course it's true."

Zhang Bo stood up in an instant: "Awesome, Mr. Wei, if this becomes a blockbuster, I need the data report of the first clinical phase, especially the toxicology test. You are in the company, I will go to get it now." material."

Soon, Zhang Bo drove to get the data prepared by Wei Kang.

"Is this a respiratory anti-inflammatory drug that I gave up before? Then I changed the direction of treatment?"

"The main ingredients have not changed, and some common drug auxiliary ingredients have been added. Is the effect so great?"

Common drug auxiliary ingredients are generally considered to have no pharmacological effects, so the first-phase clinical data can still be used, and now only a second-phase clinical test is required.

The first phase of the clinical test is to test the safety and tolerance of the human body, the second phase is to test the safety and basic efficacy, and the third phase is basically to expand the sample test on the basis of the second phase.

The sample data required for the first phase and the second phase is not much, so the time can be very fast.

It’s just that Zhang Bo has been in this business for a long time, and he has never seen such a big change in the direction of drug research in any pharmaceutical company.

However, he instantly thought of the magic drug Viagra.

Well, it's not unacceptable, after all, Viagra is in the lead, heart medicine can become a magic medicine for strengthening yang, and it seems more likely that this anti-inflammatory drug will become an anticancer drug.

He cheered up, nodding repeatedly while flipping through the data.

"Don't worry, the data of the first phase is very complete. I will give you the second clinical phase today, and I will give you the data report within a week."

(End of this chapter)