I can extract side effects.
Chapter 265 Significant progress, negotiations broke down
Chapter 265 Significant progress, negotiations broke down
After Wei Kang finished the video conference, although he was very sure of reaching a settlement, he still felt uneasy.
He always felt that the other party seemed to be hiding something, quietly holding back his big move.
There is one thing that puzzles him, why the other party has been willing to settle out of court, is there another deep meaning behind this?
If you just want money, wouldn't it be a better choice to directly sue for compensation like other infringed companies?
Why do we have to negotiate with Sanqing out of court again and again?
Why not just leave with a huge sum of $20 billion?
Could it be that the other party also needs the market for Sanqing's thalassemia gene medicine?
So you don't want to clear the venue early in the morning and quit completely?
After all, expanding the market, developing and maintaining patients consumes a lot of resources.
Although Sanqing has tightened the supply of genetic medicines during this period, the appointments and treatments of early patients have not been stopped, and are still proceeding in an orderly manner.
And these materials, together with the previous clinical trial data, can serve as a valuable reference for latecomers.
The so-called crossing the river by feeling the stones, since there are stones to touch, no one will let go of this opportunity of prostitution.
Wei Kang pondered for a while, and finally solved a little bit of confusion.
But there was one more thing he still didn't want to understand.
This seems unreasonable. The Broad Institute is just a scientific research institution. Although it also has a biotechnology company under its name, it does not have the strength to develop large-scale clinical drugs.
unless?
Dry wood meets fire.
Suddenly, Wei Kang's heart moved, and he remembered something that the other party's lawyer had inadvertently said.
"...my client recently entered into a partnership agreement with Pfizer for up to $15 billion..."
That's right!It's Pfizer!
Wei Kang was startled instantly, and a layer of cold sweat broke out on his forehead.
He only thought that he was delaying time, but he didn't expect the other party to have the same idea.
If Pfizer and the Broad Institute were teaming up to develop a gene drug for thalassemia, it would all make sense.
Just like the cooperation between Sanqing and Syngenta, one side produces genomic technology, the other produces clinical medicine technology, a strong alliance.
The most important thing is that with the lonely stone of Sanqing leading the way and crossing the river by hand, the same thalassemia gene medicine can definitely be produced.
What?You say this is a generic drug?
But the patent for gene editing technology is in the hands of the Broad Institute.
As long as Sanqing uses the Great Forbidden Technique, it will be useless even if Sanqing registers the patent of the drug.
A crime of illegal infringement is enough to deprive a patent of its legitimacy.
And Pfizer can make adjustments in the details, make a facelift, and return as the king of the original research drug.
After Sanqing was kicked out, he directly vacated the cage and changed the bird, obtained all the developed patient resources, and occupied the entire market in one fell swoop.
This trick is really fucking wonderful!
The co-author market is developed by Sanqing, patients are treated by Sanqing, and drugs are developed by Sanqing.
As a result, Sanqing was immediately banned and sent away as soon as a big pot of patent infringement came down.
All subsequent gains will be laughed at by Pfizer and the Broad Institute, and maybe they will triumphantly scold the idiots at the celebration banquet.
If he hadn't been the victim, Wei Kang couldn't help applauding the opponent's wonderful operation.
Although all this is just speculation and has not been confirmed.
But Wei Kang knew that he couldn't wait like this forever, he had to take the initiative.
Since the other party has such an idea, it cannot be allowed to succeed.
It is imperative for a strong man to break his wrist.
"Hey, why don't you just quit the Yingguo market and fight to the death with you!"
Wei Kang felt annoyed in his heart, and made a decision almost instantly.
At this moment, the phone rang suddenly.
At first glance, it was Tang Que's call.
Immediately connected, before speaking, I heard a hearty laugh, and at the same time there was a noisy background sound, as if someone was yelling.
"Hahaha, boss, we succeeded!"
Tang Que's voice was extremely excited, and he shouted like offering a treasure: "We have discovered a new gene-editing protease, boss, come and see it!"
"What? That's great! Someone will give you a pillow when you're sleepy!"
call!
Wei Kang was refreshed, stood up suddenly, and ran downstairs to the genetic laboratory.
******
Meanwhile, Pfizer's rare disease division.
A group of company executives and medical experts gathered together, all staring intently at the screen of the electron microscope in front of them.
The image above shows a cell culture dish.
The chief scientific officer, Dosten, was dressed in a white coat, dancing with excitement.
"Gentlemen, this is a sample of a patient with thalassemia. We have prepared a guide RNA that can specifically bind to the base sequence of the target DNA, and combined it with the special CRISPR- In the Cas9 plastid, a thalassemia gene drug was made."
"Then, we injected the drug into the patient's blood stem cells, and magic happened."
"The nascent hemoglobin has turned into a normal cake shape, and the hemoglobin concentration has also increased significantly. We can then implement clinical treatment on patients."
"Believe me, when the results come out, we will have another strong player in our drug family."
There was a burst of warm applause, and everyone was elated and overjoyed.
However, if Tang Que was here, he could easily find out.
The structure of the CRISPR-Cas9 plastid and guide RNA of this gene drug looks very familiar, and it is almost the same model as Sanqing's gene drug.
I can't say they are exactly the same, only that they are very similar.
******
Soon, Zheng Feng learned the good news.
The clinical trial of the first patient has also been successfully completed. The patient feels good after taking the drug, and the hemoglobin index has returned to normal. Except for a little adverse reaction, it can be said to be quite successful.
Next, Pfizer will conduct follow-up clinical Phase I and Phase II trials.
Since there is Sanqing's clinical data in front, they will do it with reference, and there will be absolutely no problems.
"Great."
Zheng Feng couldn't help but clenched his fist and waved it a few times in the air, feeling refreshed all over.
The cooperation with Pfizer finally bears fruitful results, and the Broad Institute also has its own blockbuster drug.
This is undoubtedly a major benefit to the promotion of CRISPR technology.
It is enough to prove that in addition to Sanqing, other companies can also make rapid breakthroughs in this area.
After the first and second phases of clinical trials are completed, this gene drug can immediately go through the fast-track application channel and be launched as soon as possible.
He has been envious of the vast market of thalassemia for a long time.
There are 3.5 million people in the world who carry the thalassemia gene, and the incidence rate in many high-incidence areas is as high as more than 10%, that is, tens of millions of potential patients, and hundreds of thousands of severe patients.
If these critically ill patients can use Pfizer's gene medicine.
One is sold for 100 million U.S. dollars. If [-] critically ill patients can use it, it will be hundreds of billions of U.S. dollars.
Even if there are only 100 critically ill patients, that is [-] billion US dollars.
Zheng Feng calculated in his mind, and was instantly shocked by this number.
He couldn't help holding his breath, his heart was beating violently.
The whole mouth is parched, and some are out of breath.
After a while, he regained his composure.
In the next second, he hopped and dialed his subordinate's phone.
"Immediately, immediately, notify the Sanqing people to stop the settlement negotiations, and at the same time let the lawyer immediately submit a patent infringement lawsuit to the court."
Having said that, the corners of his mouth twitched, his brows raised, and his face was filled with uncontrollable pride.
"I guess, when the young rich man in China heard the news, the expression on his face must be very exciting!"
(End of this chapter)
After Wei Kang finished the video conference, although he was very sure of reaching a settlement, he still felt uneasy.
He always felt that the other party seemed to be hiding something, quietly holding back his big move.
There is one thing that puzzles him, why the other party has been willing to settle out of court, is there another deep meaning behind this?
If you just want money, wouldn't it be a better choice to directly sue for compensation like other infringed companies?
Why do we have to negotiate with Sanqing out of court again and again?
Why not just leave with a huge sum of $20 billion?
Could it be that the other party also needs the market for Sanqing's thalassemia gene medicine?
So you don't want to clear the venue early in the morning and quit completely?
After all, expanding the market, developing and maintaining patients consumes a lot of resources.
Although Sanqing has tightened the supply of genetic medicines during this period, the appointments and treatments of early patients have not been stopped, and are still proceeding in an orderly manner.
And these materials, together with the previous clinical trial data, can serve as a valuable reference for latecomers.
The so-called crossing the river by feeling the stones, since there are stones to touch, no one will let go of this opportunity of prostitution.
Wei Kang pondered for a while, and finally solved a little bit of confusion.
But there was one more thing he still didn't want to understand.
This seems unreasonable. The Broad Institute is just a scientific research institution. Although it also has a biotechnology company under its name, it does not have the strength to develop large-scale clinical drugs.
unless?
Dry wood meets fire.
Suddenly, Wei Kang's heart moved, and he remembered something that the other party's lawyer had inadvertently said.
"...my client recently entered into a partnership agreement with Pfizer for up to $15 billion..."
That's right!It's Pfizer!
Wei Kang was startled instantly, and a layer of cold sweat broke out on his forehead.
He only thought that he was delaying time, but he didn't expect the other party to have the same idea.
If Pfizer and the Broad Institute were teaming up to develop a gene drug for thalassemia, it would all make sense.
Just like the cooperation between Sanqing and Syngenta, one side produces genomic technology, the other produces clinical medicine technology, a strong alliance.
The most important thing is that with the lonely stone of Sanqing leading the way and crossing the river by hand, the same thalassemia gene medicine can definitely be produced.
What?You say this is a generic drug?
But the patent for gene editing technology is in the hands of the Broad Institute.
As long as Sanqing uses the Great Forbidden Technique, it will be useless even if Sanqing registers the patent of the drug.
A crime of illegal infringement is enough to deprive a patent of its legitimacy.
And Pfizer can make adjustments in the details, make a facelift, and return as the king of the original research drug.
After Sanqing was kicked out, he directly vacated the cage and changed the bird, obtained all the developed patient resources, and occupied the entire market in one fell swoop.
This trick is really fucking wonderful!
The co-author market is developed by Sanqing, patients are treated by Sanqing, and drugs are developed by Sanqing.
As a result, Sanqing was immediately banned and sent away as soon as a big pot of patent infringement came down.
All subsequent gains will be laughed at by Pfizer and the Broad Institute, and maybe they will triumphantly scold the idiots at the celebration banquet.
If he hadn't been the victim, Wei Kang couldn't help applauding the opponent's wonderful operation.
Although all this is just speculation and has not been confirmed.
But Wei Kang knew that he couldn't wait like this forever, he had to take the initiative.
Since the other party has such an idea, it cannot be allowed to succeed.
It is imperative for a strong man to break his wrist.
"Hey, why don't you just quit the Yingguo market and fight to the death with you!"
Wei Kang felt annoyed in his heart, and made a decision almost instantly.
At this moment, the phone rang suddenly.
At first glance, it was Tang Que's call.
Immediately connected, before speaking, I heard a hearty laugh, and at the same time there was a noisy background sound, as if someone was yelling.
"Hahaha, boss, we succeeded!"
Tang Que's voice was extremely excited, and he shouted like offering a treasure: "We have discovered a new gene-editing protease, boss, come and see it!"
"What? That's great! Someone will give you a pillow when you're sleepy!"
call!
Wei Kang was refreshed, stood up suddenly, and ran downstairs to the genetic laboratory.
******
Meanwhile, Pfizer's rare disease division.
A group of company executives and medical experts gathered together, all staring intently at the screen of the electron microscope in front of them.
The image above shows a cell culture dish.
The chief scientific officer, Dosten, was dressed in a white coat, dancing with excitement.
"Gentlemen, this is a sample of a patient with thalassemia. We have prepared a guide RNA that can specifically bind to the base sequence of the target DNA, and combined it with the special CRISPR- In the Cas9 plastid, a thalassemia gene drug was made."
"Then, we injected the drug into the patient's blood stem cells, and magic happened."
"The nascent hemoglobin has turned into a normal cake shape, and the hemoglobin concentration has also increased significantly. We can then implement clinical treatment on patients."
"Believe me, when the results come out, we will have another strong player in our drug family."
There was a burst of warm applause, and everyone was elated and overjoyed.
However, if Tang Que was here, he could easily find out.
The structure of the CRISPR-Cas9 plastid and guide RNA of this gene drug looks very familiar, and it is almost the same model as Sanqing's gene drug.
I can't say they are exactly the same, only that they are very similar.
******
Soon, Zheng Feng learned the good news.
The clinical trial of the first patient has also been successfully completed. The patient feels good after taking the drug, and the hemoglobin index has returned to normal. Except for a little adverse reaction, it can be said to be quite successful.
Next, Pfizer will conduct follow-up clinical Phase I and Phase II trials.
Since there is Sanqing's clinical data in front, they will do it with reference, and there will be absolutely no problems.
"Great."
Zheng Feng couldn't help but clenched his fist and waved it a few times in the air, feeling refreshed all over.
The cooperation with Pfizer finally bears fruitful results, and the Broad Institute also has its own blockbuster drug.
This is undoubtedly a major benefit to the promotion of CRISPR technology.
It is enough to prove that in addition to Sanqing, other companies can also make rapid breakthroughs in this area.
After the first and second phases of clinical trials are completed, this gene drug can immediately go through the fast-track application channel and be launched as soon as possible.
He has been envious of the vast market of thalassemia for a long time.
There are 3.5 million people in the world who carry the thalassemia gene, and the incidence rate in many high-incidence areas is as high as more than 10%, that is, tens of millions of potential patients, and hundreds of thousands of severe patients.
If these critically ill patients can use Pfizer's gene medicine.
One is sold for 100 million U.S. dollars. If [-] critically ill patients can use it, it will be hundreds of billions of U.S. dollars.
Even if there are only 100 critically ill patients, that is [-] billion US dollars.
Zheng Feng calculated in his mind, and was instantly shocked by this number.
He couldn't help holding his breath, his heart was beating violently.
The whole mouth is parched, and some are out of breath.
After a while, he regained his composure.
In the next second, he hopped and dialed his subordinate's phone.
"Immediately, immediately, notify the Sanqing people to stop the settlement negotiations, and at the same time let the lawyer immediately submit a patent infringement lawsuit to the court."
Having said that, the corners of his mouth twitched, his brows raised, and his face was filled with uncontrollable pride.
"I guess, when the young rich man in China heard the news, the expression on his face must be very exciting!"
(End of this chapter)
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