Hand rubbing nuclear fusion live in the wilderness

Chapter 558 The experimental subject who was starved to death
Through the yeast alanine transfer ribose experiment, Won quickly grasped the basic structure of the RNA in the cell telomere modifier.

This is a kind of ribonucleic acid with quite a lot of base types and a rather complex sequence structure, containing twelve kinds of guanine, adenine, thymine, uracil, 5-cytosine methyl, 5-hydroxymethylcytosine, etc. A chain of molecular groups of bases.

For example, there are four more of the eight found in various countries, and their structures are unprecedentedly complex.

After determining the basic structure of this RNA, Won named it 'telomere ribonucleic acid', or 'dlRNA' for short, according to its use.

He doesn't do much research on biological genes, and some biological knowledge in his mind comes from systematic transmission, but he still knows some basic things.

The secret of allowing cell telomere modifiers to regenerate cell telomeres lies in the structure of these bases. Compared with ordinary RNA, this dlRNA contains DNA-specific thymine bases, which should be its special place , but it is very difficult to observe how this newly purchased macromolecular riboprotein makes cell telomeres grow.

Huaguo is stuck at this step. Huaguo does not have a way to observe RNA, such as changing the permeability of the cell membrane with hydrochloric acid, allowing the dye to enter the cell and attach to the designated structure.

Just like methyl green solution can make DNA green, and pyro red solution can make RNA red.

But basically to observe the nanoscale internal structure of DNA and RNA, the methods used will kill the cells, and only the cells that survive normally have the ability to divide.

Therefore, observation methods such as fluorescent staining are directly blocked in the way of newly generated macromolecular riboproteins.

But for the South Korean won, this is not so difficult.

After analyzing the main components of macromolecular riboproteins, he directly marked the materials required for the synthesis of macromolecular riboproteins with specific elements, and then observed them through the biological structure electron microscope.

These materials with specific elements attached can be clearly seen under the action of a microscope, and it can also be seen how dlRNA combines the materials step by step.

Through experimental observation of these replicated telomere-modified RNAs, Won discovered how the RNAs work.

After entering the cell, it allows the mRNA in the nucleus of the cell to change the base template structure in the mRNA when it synthesizes substances.

It is equivalent to the structure that was originally AABBCCCDD, but now it has become ABBAFFGGCCDD, with insertions and deletions.

"By compiling the original RNA information, rewriting the structure of the original target and then synthesizing the riboprotein that can promote the growth of telomere cells?"

In the biological laboratory, Won observed the activities of microorganisms fused with dlRNA through a special microscope.

It was found that this kind of dlRNA exists in the cell fluid like an intermediate station. It intercepts a part of the microbial RNA, then rewrites the bases of this part of the RNA, and then passes it out to the original rRNA for replication to generate riboprotein , enter and transport to the cell telomere.

Having determined how this dlRNA works, all that remains is experimentation and observation.

Won has found a lot of creatures, from microbes and bacteria, to white mice and rabbits, to monkeys and orangutans
All kinds of experimental organisms were gathered in the base, and then they were uniformly injected with the dlRNA living body solution.

It is known from Huaguo that all organisms cannot survive for 48 hours after being injected with this dlRNA, which is a certainty.

It's just why he can't live for more than two days is still unknown.

What Won needs to do is to find out this reason, and only then can he find the substance to make up for this defect in the remaining cell telomere modifiers.

After all, there are many types of new substances in the cell telomere modifying agent, and he has already started a large number of replication and experiments on these new substances.

Using various means and equipment to determine the purpose and structure of these things, and then cooperating with the cause of the death of the living body after injecting dlRNA, theoretically, it is possible to find out which new substance is playing a compensatory role.

To dissect a brand new drug, although this method is more complicated and the process is longer, it can accurately determine the ingredients in the drug and the corresponding effects.

"Sure enough, deaths began to appear."

Twelve hours passed, and in the biological laboratory, Han Yuan observed the experimental samples injected with the dlRNA living body solution.

Twelve hours passed, and these samples began to die one after another.

The first to die are tiny microorganisms, and then gradually evolved to insects such as fleas, ants, and butterflies.

These smaller creatures didn't even survive twelve hours.

As time went by, small vertebrates such as mice, frogs, squirrels, and small fish began to die one after another, and the death time was about 24-36 hours after the injection of the drug.

At 36 hours, all large animals began to die one after another. Even the super-large animals such as elephants, whales, and giraffes in the biobank did not survive for 48 hours.

Just like the data provided to him by Hua Guo, none of the animals injected with dlRNA could live beyond 48 hours.

Looking at these dead animals, there was also a commotion in the live broadcast room.

[Fuck, are they all dead? 】

[What is the anchor doing, researching biological viruses? 】

[Is this too painful?His body was twitching and his expression was distorted before he died. 】

[In troubled times, kill the Virgin first! 】

[In the biological laboratory, it is normal to use small white mice, white rabbits, and rhesus monkeys for experiments. Without these animals, the pharmaceutical industry cannot make progress. 】

【No, kill the Bitch first! 】

[The vaccines you take, the cold medicine you take, and the hanging bottles you hang all have to go through animal experiments before clinical trials. More than one million rhesus monkeys die in the pharmaceutical industry every year. 】

[But there are not only white mice and rhesus monkeys here, but also rare animals such as elephants, giraffes, and tigers. Isn’t there a small white mouse?Why use these animals? 】

[There is a big difference between a mouse and a human body. If you are researching drugs, it is most appropriate to use monkeys and gorillas for experiments, and the genes of those two are very similar to humans. 】

[Goodness, goodness, let the old man come to cross over. 】

[Transfer to the stomach? 】

【Caring for small animals is everyone's responsibility. For example, I have to have meals! 】

[I'm rather curious, what exactly is the anchor researching, is it a virus?They all died in less than two days after the injection of the medicine. There are super-large animals such as elephants and whales in it. Is the toxicity a bit too strong? 】

[The biological research laboratories in the United States often do these things, and I suspect that they are responsible for the pleasure that has lasted for several years. 】

[Don't doubt it, it is!Rice people are afraid to get vaccinated, for fear of being treated as experimental subjects. 】

The deaths of various experimental subjects aroused heated discussions in the live broadcast room.

Many viewers of the Heart of Notre Dame stood up and condemned, feeling that this was too cruel.But for Han Yuan, he didn't even want to pay attention to this group of idiots.

It is not unreasonable to kill the Virgin first in troubled times.

Soon, the data of various experimental subjects was collected and presented to Han Yuan.

From these data, after injecting dlRNA live samples, the order of death of the experimental subjects was according to their size.

Smaller creatures die faster, and larger creatures die more slowly.

However, this is not absolute. In hundreds of biological experiments, there have been some small-bodied animals that move longer than large-bodied animals.

The most obvious are two groups, one is the ruby-throated hummingbird, and the other is the gull bird.

The two groups of subjects were all birds, and their survival time exceeded 36 hours, which was much higher than that of creatures of this size.

"Xiao Ling, is there any abnormality in the experimental environment data of the two groups of experimental subjects, the Rufous-throated Hummingbird and the Floating Gull?"

Looking at the two sets of abnormal data, Han Yuan rubbed his chin and asked.

"There is no abnormality. The living environment of all the experimental subjects is based on the most suitable ecological environment for the experimental questions. However, compared with other experimental subjects, these two groups of experimental subjects consume more food and have lower body temperatures. "

"The body temperature of the ruby-throated hummingbird was once as low as 32 degrees during the observation experiment, and the lowest temperature of the floating gull was 36 degrees."

Xiao Ling's voice sounded in the biological laboratory, Han Yuan was stunned for a moment, and a flash of light suddenly flashed in his mind.

After quickly flipping through the basic biological knowledge, the information of the red-throated hummingbird and the floating gull appeared.

These are two birds with a strong digestive capacity and both are relatively small in size.

Ruby-throated hummingbirds, the smallest birds on Earth, eat mostly liquid nectar and need three times their body weight in food per day.

That might not sound like a lot, but if humans had the metabolic rate of a ruby-throated hummingbird, they would consume about 15 calories a day, which is about 70 times more than most people eat.

That is to say, if you eat a bowl of white rice for one meal now, it can meet your activity needs for one morning or one afternoon, but if you have the metabolic speed of a red-throated hummingbird, then you have to eat seventy bowls for one meal.

It can be said that the ruby-throated hummingbird is eating almost most of the time, and its digestion ability is very strong.

As for the Float, the digestion ability is also stronger than that.

When the gull bird eats fish, the head of the fish has been digested in its stomach when the tail is still exposed from the mouth.

Correspondingly, the extremely strong digestion ability brings great energy.

For birds, more than 70.00% of the energy obtained through food is converted into heat to maintain a normal body temperature.

But a large amount of food consumption, in exchange for a drop in body temperature.

This is very unscientific.

There must be a lot of energy somewhere else.

"Xiao Ling, let's dissect some of these dead test subjects to determine their physical conditions and see if there are any signs of cell atrophy or excessive energy consumption."

Han Yuan's intuition was obvious. When a large amount of food consumption could not maintain the body temperature of the ruby-throated hummingbird, he immediately thought of a possibility.

Soon, the anatomical data of these experimental subjects came out.

(End of this chapter)