I can see the status bar

Chapter 973 - 11D-day
The Yunhe City Health Commission announced that as of 10:24 on the 41th, the nucleic acid testing of all samples had been completed.Through the comprehensive research and judgment of national, provincial and municipal expert groups on the results of patient observation, clinical manifestations, and laboratory tests, 2 cases of pneumonia with new coronavirus infection were initially judged, of which 7 were discharged from hospital, 1 were severely ill, and [-] died. The remaining patients are in stable condition.

All 739 close contacts, including 419 medical staff, have been under medical observation, and no related cases have been found.

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Sun Lien thought he was mentally prepared for the fact that the test results of the PCR kit might not be good.In other words, he feels that he has the ability to maintain a relatively optimistic attitude when facing bad results.

But it turned out that he was still a little too optimistic about himself, and a little optimistic about the results of the PCR kit.

A total of twelve samples were sent from Yunhe.These samples have been tested by mNGS and PCR and proved to be positive samples.Eight of them had been examined by electron microscopy, and all of them were detected with the new coronavirus.

However, the PCR kit produced by Sun Lien's laboratory was only positive for six of the samples.The effective rate is only 50%.The only consolation is that the kit only showed six false positive results for the fifty control groups of distilled water.

"This kind of thing is simply murder for money!" In the office, Sun Li'en performed a "frenzy" to Dr. Pascal who came to "inquire about the news".He smashed a thick stack of documents directly on the wall of his office, and then brought down the large stack of copy paper by the way, and brought down the wall clock hanging on the top of Sun Lien's office wall.

The wall clock hit the ground, and the internal organs were scattered all over the ground.

"Finished venting?" Dr. Pascal sat on the seat, looked down at his watch and urged, "The remote video conference will start in 10 minutes, I suggest you hurry up."

Sun Lien's laboratory project has officially applied for an emergency project license for the development of PCR kits since yesterday afternoon.And 10 minutes later, they will make the first comprehensive report on the urgently applied projects.

It has a 50% accuracy rate for positive samples and a 12% false positive rate!Sun Li'en really couldn't figure it out, he would have to have some face to show this data, and then tell all the departments that supported his laboratory - this is the result of your support.

No face!
"I'm ashamed to go." Sun Lien shook his head and slumped on the seat. "What is this thing made? Such an accuracy rate, what a waste of chicken feathers? This accuracy rate, why not just throw this thing away, and use all the money to buy mNGS!"

"You are asking too much for a new product." Dr. Pascal smiled and patted Sun Lien on the shoulder, "I have also made this kind of kit in a laboratory in the United States before. Guess what, we are officially put into use How much detection specificity does the commercial product have?"

"How much? 80%?" Sun Lien asked, this number is his minimum requirement for his laboratory kit.

"65%, the false positive rate is 15%." Dr. Pascal said earnestly, "This is the result of repeated improvements in our entire laboratory for a year and a half. In order to make this thing officially put into use, we finally changed it in the instructions How to use - There are three kits in one kit. If the results of the two kits are inconsistent, you need to use the third kit for supplementary testing. The final results refer to the results of the two kits that are consistent."

He smiled and picked up the materials that Sun Lien had thrown on the ground, as well as the wall clock with his internal organs scattered all over the floor, "Your requirements are too high, which clearly shows your lack of experience—for a newly born In terms of kits for a week, your requirements are too high to be unrealistic."

"I can't handle this kind of thing." Sun Li'en said frustratedly, "No matter how long this thing has been born, it is useless!"

"It's useless now." Dr. Pascal emphasized the word "now". "Electromagnetic induction was not very useful when it was first discovered. When the electric light was first invented, it could only be used for a few minutes." They are useless for an hour. They were not useful at the time, but it does not mean that they are worthless." He stood up and stretched, "You are too nervous."

"Then what should I say when the meeting is held?" Sun Li'en asked with a bitter face, "We said we deployed ahead of time and went all out, and ended up with such a crap thing?"

"There are probably two other colleges and universities that are working on this kit like us, and there are probably five companies." Dr. Pascal was well informed, and he said to Sun Lien, "During today's meeting, you can listen to them first. What kind of progress is it?"

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"Our current products can achieve a certain degree of specificity, but the false negative rate is still relatively high...according to our current calculations, it is about 45%." In the video conference, several colleges and universities did not even have finished products. They just briefly mentioned that they are starting to design primers, and then there is no more.As for the finished products, there are currently only three including Sun Lien's laboratory.The product of one family went the wrong way completely. They made quick test strips.

It’s not that the quick test strip is impossible, but because of its detection principle, this kind of thing is essentially not suitable for controlling such a large-scale infectious disease-its false negative rate is too high, and it is theoretically impossible. Possibility of narrowing controls.

But at present... of all the testing products proposed at this meeting, it seems that Sun Lien's laboratory has the best results and is closest to the usable level.

"This product of Ningyuan Medical College is currently the most advanced." The person who made the speech and report on behalf of Sun Lien's laboratory was naturally Shen Xi who was so nervous that he kept hiccupping.After listening to his report, after a while, the capital expert who presided over the meeting pushed his glasses and said, "I read the information, you have already found a cooperative company to start the trial production of the first batch of test kits, right? Try it." How is the testing effect of the product?"

50% accuracy, plus a 12% false positive rate is not a good result, especially for a product that is still in the laboratory development stage.But now the time is too tight. After obtaining the sequencing, the relevant departments began to ask the colleges and enterprises to develop related products, and it took only two days before and after the first test.It is not easy to produce qualified primers in these two days.

"Eh..." Shen Xi was stunned for a while, then quickly lowered her head and flipped through the documents.After more than ten seconds, he raised his head and said with a confused face, "The data we are providing now is the data of the first batch of trial kits."

The experts in the capital were silent for a few seconds and then asked, "Then what are your laboratory data?"

"75% accuracy rate, 6% false positive rate." Shen Xi replied with some embarrassment, "We are actively improving the primer system, and strive to increase the accuracy rate to more than 90% as soon as possible."

(End of this chapter)