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Chapter 950 Decision

Chapter 950 Decision

In the end, the professor still couldn't get out of the private room by himself - he was helped out by someone.

In front of Liu Tangchun, dig out Liu Tangchun's favorite disciple in front of Dean Liu.If Old Comrade Liu didn't respond at all, wouldn't that weaken his reputation as a "big excavator"?

Even if Old Comrade Liu asked you to ask, you would have to be force-fed after the question is over.

Because his surname was Jia, Professor Jia Xifeng, who was determined not to allow others to call him by his surname, was helped out of the private room like a soft noodle.Professor Xifeng kicked his legs limply on the ground, and at the same time insisted that Liu Tangchun give himself an "excuse", roughly the content is like this, "Liu Tangchun! You bastard! You are unreasonable, you are lying people!"

Although he couldn't speak clearly, the grief and indignation of "betrayed and plotted against" was actually conveyed to the ears of every expert present, and caused roars of laughter again and again.

Professor Jia was thrown into a taxi, and then the two review experts who lived in the same hotel as Professor Jia decided to go back with Lao Jia, so that they could take care of him.But Sun Li'en was stopped by Liu Tangchun who smelled of alcohol.

"Your application for joining the party has been approved by the organization, and then you will enter a one-month publicity period. After the publicity period, you will be inspected as a probationary party member for one year, and you can officially join the party." Liu Tangchun yawned, and then said to Sun Lien , "I went to the dean's office yesterday and got an mNGS for our comprehensive diagnostic center."

Sun Lien didn't pay much attention to the first half of the content, but the following news attracted his full attention, "mNGS? What is it? What's the matter? It's for us?"

No wonder Sun Lien is so excited. As the ultimate means of detecting infection, mNGS can play a clinical role that cannot be underestimated.But if this device wants to enter the hospital, what needs to be overcome is not the problem of "expensive".

Although an mNGS device itself is not cheap, it is not "expensive" for a tertiary hospital.The pre-processing equipment plus the mNGS equipment itself will generally not exceed 400 million yuan.

400 million is certainly not a small amount for an ordinary family, but for a comprehensive tertiary hospital, this fee is far from the point of "must be cautious".The price of one ECMO is about 150 million, but the role that mNGS can play is not comparable to that of two and a half ECMOs.

mNGS stands for metagenomic sequencing technology of unknown pathogens.It is a technology based on metagenomics and high-throughput sequencing technology that can detect and analyze all known and unknown pathogens in samples from various clinical sources.It is suitable for the identification and detection of various pathogens, especially unknown new pathogens.It has outstanding clinical reference value in the laboratory diagnosis of new sudden, complicated and mixed infections.

Sun Lien himself has performed several mNGS tests in clinical practice, and indeed obtained quite important clues and hints from them.However, in the past, mNGS was used most of the time because the patient was seriously ill and the pathogen could not be identified immediately by conventional channels.When there is no other way, he will consider sending patient samples to a laboratory with mNGS testing capabilities for testing.

And this "other" laboratory often lacks a unified standard capability.Some testing companies promise to complete the testing and analysis of samples within 24 hours and issue a report.And some companies need 36 hours or even 48 hours to give the corresponding results.At the same time, different testing companies and laboratories have different genetic databases for analyzing and comparing pathogens.The difference in databases actually determines the different detection sensitivities of different laboratories.This may also negatively impact the patient's test results.

At the same time, since the test samples do not need to be cultured, there is no need to make assumptions about the test items. The "all-in-one" detection method of mNGS equipment will not only detect microbial nucleic acids in test samples, but also detect microbial nucleic acids in containers, environments and reagents.This will directly increase the difficulty of judging the detection results and interfere with the detection accuracy.For those companies conducting commercial testing, aerosol contamination and other microbial effects are almost inevitable.

If these devices can be purchased by the hospital and put into use, this problem may be avoided to a large extent.

But... the reason why this kind of cheap and useful equipment is not widely purchased by hospitals is that they still have serious "defects".

First, human operations are required for nucleic acid extraction, library construction, library quantification, and magnetic bead purification from samples.And as long as it is related to "people", it means that there will be a steady stream of labor costs, the probability of detection failure, and the possibility of contaminated samples.Afterwards, the analysis of the output results requires the hospital to have an at least "usable" database for comparison.If you want to improve this database step by step from scratch, it may take dozens or hundreds of excellent genetic experimenters to spend several years or even longer to do it.

At the same time, in order to perform mNGS testing in a hospital, you first need to have a "clinical cytology and molecular genetics major" treatment subject license, a safety laboratory record certificate of level two or above, and you must also obtain a clinical gene expansion testing laboratory technical acceptance certificate .

In other words, in order for Ningyuan Fourth Central Hospital to carry out the mNGS testing project, the Laboratory Department needs to recruit a group of testing physicians with relevant professional abilities and skills.And it is necessary to "get" a database with characteristics of at least [-] pathogens.Finally, it needs to be in a laboratory that complies with the "Regulations on the Biosafety Management of Pathogenic Microorganism Laboratories", "Technical Specifications for the Construction of Biosafety Laboratories", "Technical Standards for the Construction of Secondary Medical Biosafety Laboratory biosafety general requirements ", "pathogenic microbiological laboratory biosafety general guidelines" position, set up laboratories.

One can imagine the difficulty of setting up a laboratory with mNGS inspection capabilities from scratch.Anyway, Sun Lien wouldn't believe it if he was killed. Such an important and troublesome matter was the result of Liu Tangchun's "going to Dean Song's office".

Without months of research, planning and research, this project would not even have been possible.Who knows how many gray hairs Liu Tangchun sacrificed for this project.

"This laboratory is placed in your comprehensive diagnostic center." Old Comrade Liu pretended to be relaxed, "If you want to use this thing well, and use it effectively, you have to put it in the most suitable place. But you can't eat alone, either. This laboratory still has to undertake testing requests from other departments in our hospital."

"Don't worry." Sun Li'en nodded solemnly, "The fourth hospital is the foundation of the comprehensive diagnostic center, and we will definitely fully cooperate with the needs of the hospital."

After saying a few words in the official language, Sun Li'en said with a smile, "I haven't taken office yet, and you gave me such a big gift. I'm really a little apprehensive..."

"A sword deserves a hero." Liu Tangchun laughed a few times before asking, and then said seriously, "Dean Song is willing to agree to this request, and that is because he has considered this issue—to keep you, we must not only have an attitude, You have to have sincerity, means, and results." He looked at Sun Lien, and then said, "I asked him to ask Lao Jia this question before."

"I guessed it." Sun Li'en said to Lao Liu with a smile, "I heard what Teacher Jia shouted when he was carried away just now."

"So? Are you still planning to stay in Ningyuan?" Liu Tangchun was rarely hesitant and uncertain. "If you go to the Shanghai stock market, I can help you connect. If you go to the capital, then you can go directly to Tongxie. These places themselves will be the easiest places for rare disease patients to seek treatment, and you will have more opportunities... "

"Mr. Liu, I signed a contract and bought a house in Ningyuan the day before yesterday." Sun Lien shook his head with a smile, "I am confident that as long as I work here seriously, the patients around me will have more and more choices. Come to Ningyuan to see a doctor." Sun Lien seldom has such a particularly confident expression, just like Liu Tangchun seldom shows hesitation, "Continue to work, why can't the country's best diagnosis center for rare and difficult diseases be in Ningyuan? ?”

 Another infusion tomorrow, I guess the inflammation index should be able to come down.

  After the re-examination the day after tomorrow and there are no problems, how about we have a blast the day after tomorrow—that is, on the 14th?Explode it in three or four chapters.

  
 
(End of this chapter)

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