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Chapter 79 High-dose atropine
Xu Yourong "properly" exaggerated the degree of poisoning of some pilots.In fact, Zhao Bo fell into a coma about 10 minutes after he was admitted to the hospital.But considering that he had been thoroughly cleaned and kept away from the toxin environment when he was admitted to the hospital, in fact, the judgment of 10 minutes is not necessarily wrong.

Xu Yourong's face didn't change, she really didn't lie - at most she just didn't make it clear that she guessed the time of coma.

Secretary Chen put down his pen, covered his eyes with his hands, slowly rubbed his sore eyes, and sighed, "Fortunately...fortunately."

Under severe weather conditions, a series of serious traffic accidents occurred on the expressway, resulting in many injuries and seven people were poisoned.This is already a very serious security incident.If the rescue helicopter had an accident during the transfer, the consequences would be unimaginable.What punishment might be imposed is not even within the scope of Secretary Chen's consideration - the plane fell from the sky, and now it is close to the rush hour for lunch, who knows how many innocent people will be killed and injured!

Secretary Chen opened his eyes, looked at Sun Lien in front of him and said in a deep voice, "Good job!"

Sun Lien was taken aback.

"Although I don't understand medicine, I also know that doctors should be more capable the longer they work." Secretary Chen seemed to be a little relieved from his fantasy, and he began to ask about Xu Yourong's situation with great interest. "You are a doctor of medicine who came back from studying abroad, and you are a student of Dean Liu. Why did you study with Dr. Sun who was trained by you?"

Xu Yourong's expression remained unchanged, "Because I think it's necessary."

"Xiao Sun has two brushes." Secretary Chen nodded, then pondered for a while, and said to Sun Li'en, "You are the first to prevent problems before they happen. But I am also very concerned about the situation of the four firefighters —how are they doing?"

"Doctor Sun went to the pharmaceutical factory to help coordinate the emergency medicine." Xu Yourong continued, "I have been staying in the emergency room, and I have a better understanding of the situation of the four firefighters. Let me tell you."

"The two firefighters sent by the helicopter had obvious symptoms of organophosphate poisoning and severe hypothermia. We estimate that the two firefighters' combat uniforms were damaged during the on-site emergency decontamination. Yes." Xu Yourong introduced, "The condition of the other two is better, and they are only showing symptoms of organophosphate inhalation poisoning. But their vital signs are fairly stable - one person has generalized muscle stiffness and symptoms of respiratory failure. We Symptomatic treatment was given."

Secretary Chen shook his head, "I don't understand this kind of words. I just want to know if the lives of these four people have been saved, and if not, when will they be saved."

This kind of remark is actually a bit unreasonable, but Sun Li'en can fully understand Secretary Chen's worries and concerns.He pondered for a while and said, "The main problem we are facing now is that there is no large dose of atropine injection. The new substitute Chang Tuoning has no stock at all. Mr. Shen from the Second Pharmaceutical Factory gave us a lot of support, and more than 50 boxes of atropine It has been moved to the pharmacy room. As long as the ampoule bottle is knocked fast enough, the lives of these four firefighters can be said to be saved by about [-]%."

Keeping 50% of his life is not Sun Lien's nonsense.There are two main causes of death from organophosphate poisoning. One is muscarinic symptoms—smooth muscle spasms and increased gland secretion caused by parasympathetic nervous system excitement, which may lead to pulmonary edema and respiratory obstruction.Nicotinic symptoms can cause respiratory paralysis and cardiac arrhythmias.The symptomatic treatment given by the emergency department and the "atropineization" caused by a large amount of atropine injection can effectively prevent the emergence and further spread of these two symptoms.Even if the disease cannot be completely relieved, doctors can still fight with advanced airway, ventilator support, and more than [-] kinds of arrhythmia drugs.

The reason why the [-]% possibility is deducted is because the four firefighters may appear, but the nerve damage and multiple organ failure that have not yet appeared.

Although relatively rare, organophosphate poisoning can cause neurological damage.When the damage occurs to a terminal nerve, the condition can manifest as partial paralysis of a limb.But if it is manifested in the parasympathetic or sympathetic nervous system, it will lead to irreversible respiratory failure-the system that should control breathing cannot effectively transmit signals, and the patient will not be able to breathe effectively unless relying on a ventilator.

The parasympathetic nerve also controls the visceral activities of the human body, the peristalsis of the gastrointestinal tract, the work of the liver, and even the heartbeat.If there is damage here, eventually the major organs of the body will go on strike completely.

It can be said that there is only one ultimate purpose in the rescue process of organophosphate poisoning, which is to avoid damage to various organs and nervous system by supporting the body system and preventing damage to cholinergic nerves.

After listening to Sun Lien's explanation, Secretary Chen was silent for a moment, and suddenly asked, "Have you met Mr. Shen from the Second Pharmaceutical Factory?"

"Yes." Sun Li'en nodded, and continued after a moment of hesitation, "Her daughter was admitted to the hospital due to an emergency yesterday, and I was in charge of the treatment. Dr. Xu performed the first exploratory operation on her."

"Why can't a batch of large doses of Atropine be produced right away..." Secretary Chen hesitated, and District Chief Ouyang Hua next to him reminded in a low voice, "Atropine."

"Yes, what about atropine?" Secretary Chen asked, "I majored in automation at university. Although it has nothing to do with pharmacy, if it is just to adjust the production dosage, it should be completed soon, right?"

The middle-aged man who has been silent next to him whispered, "Changing the production line may cause very serious impact and losses on the company."

"You can't put human life aside just to make money, can you?" Secretary Chen was a little angry, but he also knew that what he said was a bit nonsense.After waving his hand, he sighed, "Anyway, thanks to you all."

"Actually..." Sun Li'en said suddenly, "Maybe I can have a chat with Mr. Shen. Maybe they can provide a batch of raw materials."

Atropine itself is a white or colorless crystalline substance that is very soluble in water.Although there are many important processes in the production of pharmaceutical factories, at its root, it is only the dissolution of pharmaceutical raw materials and then aseptic filling.

Sun Li'en's suggestion is tantamount to moving the production workshop of atropine to the hospital.Dissolve atropine API directly in the hospital to make urgently needed large doses of medicine to meet urgent needs.

Xu Yourong suddenly became anxious.She tugged on Sun Li'en's clothes, her eyebrows were raised upright, "Are you crazy?"

(End of this chapter)