I can see the status bar

Chapter 726 Finding Direction
There is definitely a possibility of genetic disease.But the question is, what genetic disease can meet this series of conditions?

Qian Hongjun was silent for a long time, "This...it's hard to say. The most similar one is of course NMO, Leber is a bit similar, but Behcet's disease can also be made up..."

Genetic diseases are a huge disease bank, and people are still able to discover various new genetic diseases to this day.There are also many kinds that can affect the central nervous system and optic nerve.From deficiencies of various key proteins or enzymes to immune diseases with genetic characteristics, almost all of these can cause the exact same symptoms as Tang Min's now.

Sun Li'en didn't expect to find out what the problem was after a consultation with Qian Hongjun.He just wrote down Qian Hongjun's opinion, and then continued to ask, "If it is some kind of genetic disease that has never been discovered...how can we be sure that it really exists?"

"Then your workload will be heavy." Qian Hongjun didn't laugh at Sun Li'en for being overwhelmed.In fact, he really felt that Sun Li'en's asking this kind of question now was not out of the ordinary - with this kid's black face, it was not completely impossible for him to encounter some kind of disease that had never been discovered before. "First of all, you have to figure out what the pathogenic factors of this disease are, that is, you have to find out its mechanism of action first. Second, you need to analyze the mechanism of action to find out which part of the patient's internal environment is the cause of the disease. The question—is it the lack of channels on the cells, or the lack of certain specific proteins or enzymes, and then based on the current known gene sequence research, reverse lock the position of the gene defect..."

Sun Li'en listened carefully and kept taking notes.Qian Hongjun looked at Sun Li'en curiously, and then said, "According to this speed, it is not impossible for three to five months at the fastest, and one to two years or even three to five years at the slowest...you can be sure whether this disease is a new discovery or not." genetic disease."

"So long?" Sun Lien was taken aback. He originally thought that this process might only take a month or two. "Can't it be any faster?"

"You need to figure out the cause of the disease first." Qian Hongjun really felt that Sun Li'en was a little overwhelmed this time. "You have to collect a suitable sample, and then analyze the sample in sufficient detail. This alone has to be a matter of luck... Anyway, I have never heard that it can be done once. This is a labor-intensive research process, who Can't save time."

Scientific research is hard work, especially when encountering such a case where nothing is certain.Repeated sampling and analysis back and forth is a basic operation. In this process, there are not a few people who get stuck for three to five years or even get stuck to give up.

Sun Li'en is really a little numb now.As fast as three to five months, as slow as one or two years or even three to five years?He does have time to spend on such things, but Tang Min...she may not have such a long time to wait.

"My suggestion is to rule out diseases in other directions first, such as autoimmune diseases and tumors." Qian Hongjun put on the steam eye mask again, "After confirming that these diseases have been ruled out, then consider genetic problems-such operability It’s stronger. If you want to deal with genetic problems first...it’s not impossible.” At this point, Qian Hongjun seemed to remember something, he pulled off the steam eye mask on his face, and sat up suddenly , "You can take a sample first, and then send it for gene sequencing!"

"That's okay? Whole-gene sequencing is expensive, right?" Sun Lien frowned and asked, "Do I have to take another biopsy for sequencing?"

"Biopsy is also okay, and peripheral blood should be okay too. Anyway, it's whole gene sequencing." Qian Hongjun seemed quite satisfied with his thoughts, "The price of this thing is cheaper than mNGS, and the speed is also very fast... I remember It will take about two weeks for the report to come out. For sampling...you just call the company that does genetic testing and ask them for testing standards."

That's a very good idea.Sun Li'en nodded, stood up and said, "Thank you Director Qian, this really helped me a lot."

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There was no one in the office, and all the doctors from the two treatment groups were sent out to arrange and accompany various examinations.Professor Zhang Zhifu has a teleconference to attend in the afternoon, so he is not in the office either.

Sun Li'en sneaked into the office like a thief, and then opened the old operation interface on his computer disguised as a desktop pet.Then it took you a full hour to input all the previous diagnostic data into the old thing's computing system.

This time the old man seemed to have encountered a hard bone. He paced back and forth on the table, holding a magnifying glass to observe carefully in the corner, and then turned his head to flip through a thick book about his height on the table. Otherwise, he squatted down and drew circles on the ground with his head covered in distress, and there was even a lot of black smoke coming out of his head—an overwhelmed look.

From the operation interface of the old thing, Sun Lien was surprised to find that the computing power occupancy rate of the computing center had risen to 80%, and it was still rising.He scratched his head in surprise, still wondering why such a large computing center would take up so many computing resources for the calculation of one case.

However, Sun Lien is not a person who likes to think about these things. Seeing that the calculation is expected to be completed in three hours, he decided to take this opportunity to contact the gene sequencing company first.

Sun Lien is not very familiar with places like gene sequencing companies. Instead, the research institutes in the school have more dealings with them.Sun Li'en didn't bother to browse the webpages one by one, so he directly called his roommate, Dr. Cao Xin's younger brother Shen Xi.

"Brother Sun, do you have any instructions?" Shen Xi answered the phone, and asked heartily, "You are coming back late tonight, do you want me to leave the door for you?"

"I guess I can't go back today, so I need the help of Shen's brother." Sun Li'en put on a pose, and then said his real purpose, "Do you have a more reliable and accurate gene sequencing company at hand?" Contact information? I have a patient here who may need a whole genome sequencing."

"Do it for people?" Even Shen Xi, who is engaged in basic medical research, was a little surprised after hearing this request. After all, what they usually do is single-point or proteomic testing. Shen Xi has never done whole genome sequencing. .Especially after hearing that Sun Lien was going to test the "patient", he didn't dare to agree casually - it might be a human life and must be taken seriously.After thinking for a while, Shen Xi said, "How about this, Brother Sun, I will contact the company I have worked with before and ask about the specific situation. Then I will ask other seniors to find a company with high test accuracy. The company gives you."

"Thank you, thank you, please." Sun Lien naturally wished for this, and in order to make Shen Xi more motivated to work, he even gave him a reward, "When I'm done with my work, my brother treats you to dinner." liquor!"

"It's fine to drink, I drink less than Senior Brother Cao." Shen Xi continued to smile heartily on the other end, as if he had completely walked out of the shadow that the previous time management master had brought to him.However, in the next sentence, Shen Xi revealed her true purpose, "Brother, you really plan to thank me, or ask sister-in-law to introduce me a girlfriend? I don't ask too much, just be gentle and considerate."

"Your sister-in-law is a nurse. If she can introduce you to a nurse, then she is also introducing a nurse." Sun Lien wanted to help Shen Xi, but unfortunately, he did not dare to say that Hu Jia had a suitable single nurse to introduce to him. he. "Besides, how can a nurse be gentle and considerate? I guess there is only one in the entire Fourth Hospital, and she is your sister-in-law. The other little nurses are the ones who can scold you for half an hour if you make a small mistake... "Sun Lien sighed, "Anyway, I invite you to dinner, and if there is a suitable girl, I will introduce it to you. Give me some snacks about the sequencing company, which may involve a human life!"

(End of this chapter)