Chapter 694
For doctors, it is a very sad thing for a patient to have no cure.But it is limited to "sad".But for the family members... this news is a bolt from the blue.

The description of "bolt from the blue" is a bit...not appropriate.Sun Li'en looked at Cao Zhiquan's son with complicated feelings.

For a young man in his early 20s, the world should still be full of hope and color.Parents are not very old. Not only can they take care of their own lives, but they can also help themselves who are just beginning to be independent.

That's the way things should be.

Xiao Cao was sitting on the seat with his hands tightly clenched into fists beside him, trembling all over, his face pale.After staring blankly for a while, he opened his mouth and asked in a trembling voice, "Really... There is nothing we can do?"

"If it is indeed Creutzfeldt-Jakob disease, there is no way." Although Sun Lien wanted to comfort the little brother in front of him, Sun Lien couldn't think of how he could comfort him at all-if the cerebrospinal fluid 14-3-3 protein is positive, then CJD can only be diagnosed with a brain biopsy.In other words, even if there is a positive report of CSF 14-3-3 protein, brain biopsy is still required for patients with a complete diagnosis.The presence or absence of relevant reports of cerebrospinal fluid will only affect the confidence of doctors when making recommendations for brain biopsy.

But in reality, it is not a simple matter to detect 14-3-3 protein.Even though the testing equipment in the Comprehensive Diagnostic Center is newly purchased, there is still no corresponding reagent that can be used to detect this protein.

Taking a step back, assuming that the Creutzfeldt-Jakob disease (CJD) suffered by Cao Zhiquan is a hereditary Creutzfeldt-Jakob disease (PID), which is relatively easy to detect, a PCR test should be performed on the patient's cerebrospinal fluid or peripheral blood samples to confirm the diagnosis. Detection of the PRNP gene coding sequence that causes the lesion.

But PCR isn’t some simple machine that does everything—you just throw a sample into the machine, sip your coffee, and wait for that high-tech-looking PCR machine to finish humming away and get the results.If it were really that simple, there wouldn't be countless biological dogs howling in the school.

To detect specific gene sequences using PCR, it is first necessary to amplify specific genes in the sample.The specific detection fragment in the sample is multiplied for [-] rounds, that is, after a billion-fold increase and replication, it can be detected by the machine.In the entire amplification process, in addition to the long wait, it is more important to find the correct primers that can amplify the specified gene structure.

PCR detection of PRNP gene encoding is a relatively mature technology, but practical difficulties still exist.The most direct difficulty lies in the design of primers.

In the complete process of amplifying the PRNP gene encoding, the most important primers are not readily available.At least the Fourth Academy, Ningyuan, and even the entire Song'an Province did not.If you want to do this kind of inspection, you can only send the samples to the relevant companies in the capital or Shanghai stock market, and entrust them with full authority to carry out the inspection.Going back and forth like this, according to the progress rate of Cao Zhiquan's symptoms, I'm afraid he has died before the result.

"Currently...we don't have any good solutions. But according to the specialist's advice, we can try hormone shock therapy." After much deliberation, Sun Lien decided to try again for Cao Zhiquan's life. "If the hormone shock therapy is effective, then he may have a disease with similar symptoms but still recoverable..."

Physicians seldom say such things to patients' families. The very word "try it out" implies uncertainty.Families of patients abhor uncertainty.But under the current circumstances, Sun Li'en had no choice but to fight against this uncertainty.

The vast majority of CJD patients die from decubitus ulcers or lung infections shortly after falling into akinetic mutism.Not to mention curing this disease, modern medicine does not even have any effective treatments that can improve their quality of life.Frequent turning over and nebulized inhalation plus vibration vest may be able to prevent bedsores and lung infections to a certain extent, but it still cannot fundamentally improve the patient's condition.

More than 50 years after humans landed on the moon, there are still a lot of diseases in the world that doctors can't deal with.Even if satellites can locate almost all users on the earth in space, when facing many diseases, we can't even see a possible solution to the problem.

Sun Lien felt very depressed.

Doctor depression is actually a very common thing.From unsatisfactory work to patients' lack of cooperation and family members' incomprehension, there are many ways to frustrate a doctor who works every day until he is about to die from overwork.Thanks to the status bar, and Sun Lien's own "good luck", the feeling of depression is actually a little... new to Sun Lien.

Freshness meant that he had little experience dealing with this feeling.The feeling of "depression" in the past was almost all because of exams and study problems.When he was a student, like everyone else, for Sun Lien, exams and study were the biggest difficulties in the world.But after he went to the clinic and started to treat patients, he realized that the frustration before...was not worth mentioning.

This feeling is not strong, but the sense of presence is too full.Looking at the back of Xiao Cao leaving slowly, Sun Li'en felt like a stone was pressed on his chest.The throat is also not very comfortable. It seems that there is a small piece stuck near the Adam's apple, and I can't even speak fluently.

For a moment, Sun Li'en even wanted to stop Xiao Cao, and then persuade him to go through the discharge procedures for Cao Zhiquan.

Although he said that he could use hormone shock therapy to give it a try, Sun Lien knew very well that such a classic and standard symptom is really unlikely to be VGKC.Cao Zhiquan's athletic ability has always been normal, and he does not have the iconic movement difficulties of VGKC.

In this case, is it necessary to continue hospitalization?Although the Comprehensive Diagnostic Center itself has the support of Takeda Pharmaceuticals, it can reduce a large part of the examination and treatment costs...but it still inevitably takes up the time and energy of the family members if they continue to live.The cost of nursing and hospitalization still needs to be paid as usual...

Is this really good?If you give up treatment and go home, the financial pressure on the family will be a little less, right?

But looking at Xiao Cao's back, Sun Li'en still couldn't say that.He knew very well that if he made such a suggestion, it would basically be equivalent to signing Cao Zhiquan's death penalty execution letter.As a family member, no matter whether Xiao Cao accepts the proposal or refuses... I am afraid there will be a knot in his heart.

A life cannot be measured by a few words.

(End of this chapter)

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