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Chapter 613 Eyes (July 7, 27 for subscription)
Intrathecal injection is a somewhat risky procedure.Clinically, intrathecal injection is mostly used in the treatment of central nervous system leukemia.Administered through the cerebrospinal fluid system, the drug can fill the subarachnoid space on the surface of the base of the patient's brain within four to six hours.This method of administration successfully avoids the shielding effect of the brain-blood barrier on chemotherapy drugs, allowing the drugs to successfully enter the circulation of the brain cisterns.Repeated administration by intrathecal injection can well maintain the concentration of the drug in the brain.

But intrathecal injections also have risks.This risk is mainly reflected in the capacity of the drug itself.The human cerebrospinal fluid can produce about 150 milliliters a day, but the cerebrospinal fluid that can be accommodated in each ventricle and spine generally does not exceed [-] milliliters.These liquids themselves can effectively support the central nervous system of the human body, and play an excellent role in buffering and removing inflammatory substances.

Impaired circulation of cerebrospinal fluid is one of the most common causes of elevated intracranial pressure.Cerebrospinal fluid produced by the abundant choroid plexus in the two lateral ventricles enters the third ventricle through the interventricular foramen, and then flows into the fourth ventricle through the midbrain aqueduct.It then drains into the subarachnoid space of the brain and spinal cord through the median and lateral foramen of the fourth ventricle, and retrieves CSF through the parasagittal arachnoid granules.This relatively complex flow system and communication system means that the entire cerebrospinal fluid circulation system is far more fragile than the blood system.Generally, during treatment, the volume of fluid that doctors can inject into the cerebrospinal fluid system at one time will not exceed 60ml.

In the previous treatment, in order to allow amphotericin B to pass through the brain-blood barrier as soon as possible and reach an effective concentration in the patient's brain, the treatment group had injected twice a total of 50ml of amphotericin B and glucose solution into all patients.The interval between the two injections was two hours.And now it has only been 10 minutes since the last injection.

Even if the patient has not received intrathecal injection of amphotericin B before, it is impossible for doctors to inject 800mg of methylprednisolone into their lumbar spine in one go.This is physically impossible.

As for problems such as kidney damage or lower limb and back pain caused by high-dose amphotericin, the doctors in the medical team don't care much about it-only living people are troubled by side effects and adverse reactions.Dead people don't complain about pain in one part of their body.

After receiving the reminder that "dihydroartemisinin and methylprednisolone can be used together for immunosuppression", Liu Tangchun quickly called the medical team and asked to send artemisinin for use as soon as possible.The intrathecal injection plan of methylprednisolone was temporarily postponed for half an hour.Methylprednisolone was administered intravenously before the artemisinin was delivered.

The next treatment process is basically to wait and see what happens. Sun Lien and Liu Tangchun, who have been busy all day, can finally find a place to squat for a while-the two have not slept since yesterday. Return to the U.S. medical team camp for diagnosis and treatment.After two days of hard work, with the support of their own people, they can finally rest for a few hours.

Sun Li'en quickly fell into a dreamless deep sleep.From the state of high mental tension to the time when you can relax and sleep, people sleep a little unsteadily.The deep sleep seemed to last only a few minutes, and when Hu Jia woke him up, Sun Li'en even felt a little wronged - can't you let me sleep for a while longer?

But when he found out that he had slept for six hours, the grievance turned into trouble. After six hours of sleep, he was still sleepy. What should he do?
"We have already contacted the country, and neither the embassy nor the State Department can help." Ms. Iweala also understands that the current situation in Politanvia is not stable.Because one of the two leaders of the military fell ill and the other suffered from alcoholism, as the current main person in charge of the camp, she needs to shoulder the heaviest burden.But the reality is cruel.Both the U.S. Africa Command and the embassy in Politanvia said they could "do nothing" to Ms Iweala.Conventional civil aviation cannot transport so many remains into the United States.

"We can't evacuate now, so we can only wait... until the matter comes to an end." Ms. Iweala looked a little frustrated, "If we can't find an institution to transport the remains, we can only... bury them here first gone."

"I can't help with this kind of thing." Liu Tangchun didn't care much about other things, he was just a little worried that the friend he had just met might be buried in a foreign land.No matter why the American soldiers will appear in this area, and they will also be responsible for the security of the camp.After all, these American doctors came to Politanvia to treat diseases and save lives. "However, I can report this matter to the Politanvian authorities. Maybe it will be useful."

Help people to the end, send Buddha to the west.After talking to the camp where he was expected to arrive today, Liu Tangchun decided to cancel today's trip.The doctors who did not reach the American camp continued to repair in the village-just happened to be able to help the local residents with medical treatment.The doctors who arrived at the American camp insisted on checking the situation for another night.If after tonight, no one died or not too many people died, then the treatment plan is effective.The rest of the work could go on to the American doctors in the camps.

If the patients are all dead...at least the medical team won't have a reason to stay any longer, right?

"The only pity is that we can't stay here for too long." Dr. Hu Chunbo was picking up the self-heating food provided by the US military on his seat.The taste of this kind of food is actually relatively ordinary, but the biggest advantage is that you can have a hot bite.In order to ensure safety, the canteen in the camp has not been in operation for nearly three days. "If I stay here for half a month, I will definitely write an SCI article, and maybe it can be sent to the second district."

"Then don't think about it." Liu Tangchun was also eating self-heating dry food, but Comrade Liu was a little uncomfortable with the menu in his hand. He complained while eating, "Americans really have never seen the world. Dumplings How can there be cheese in it!" After throwing down the self-heating food in his hand, Liu Tangchun rubbed his hands on the side wall without caring about his image, "If you want to post an article, you still have to come to our fourth courtyard. Look at Xiao Sun , Just after a year of regular training, New England published an article."

The case report on the collaboration between Sun Lien and Xu Yourong has been pre-published on New England.Cheng Wen's condition has aroused the interest of many industry experts.Although the contact information in the article is Xu Yourong's email address, Sun Lien has also received many calls from across the ocean these days.The number of people who called Sun Lien was getting bigger and bigger, from professors of well-known medical schools to experts in the industry.There is only one question that everyone is most concerned about, "Can that little girl come to us for an immunization test?"

Like Liu Pingchuan's estimate, ordinary doctors would probably only think that this case looks a little scary.But at the level of experts in the industry, the first thing everyone cares about is "why".Why do other people's brain hydatids expand like blowing air, but Chen Wen's case showed 27 small white spots in the brain.If they can figure out what makes Chen Wen's case different from other cases, doctors may be able to find treatments that can be applied to other brain hydatid infections.At least some means of inhibiting the growth of hydatid cysts could be found.

This is of great significance, and it is no wonder that the gang of domestic bigwigs who are jealous of the National Natural Science Project are trying their best to get ahead.

"New England?!" Hu Chunbo's eyes changed again, and he unconsciously looked at Sun Li'en, full of envy and jealousy.It's like... It's like seeing an SCI article that no one signed.

(End of this chapter)