I can see the status bar

Chapter 398 Blood Transfusion Between Relatives
Dean Wu's problem has been temporarily resolved.But in the past three days, the most important key event has not progressed too smoothly - Hou Huiying's liver is rapidly failing.Her husband Tang Xingde and son Tang Wen are in stable condition.Tang Wen even has no respiratory symptoms, and he looks good now.He could even get off the hospital bed, walked to his mother's bed, and looked at her worriedly.

Hou Huiying's condition is not good, very bad.Although Wu Youqian made a decisive decision, although Director Xiong successfully completed the extremely difficult percutaneous transhepatic portal vein and gastric fundus vein embolization to stop bleeding.But the arrival of DIC still dealt a great blow to Hou Huiying's already weak body.Speaking of which, thanks to the independent Department of Hematology and Transfusion Medicine in the Fourth Hospital, it was possible to temporarily stabilize her vital signs.

It is no joke that DIC has a mortality rate of more than 50% in a tertiary hospital without these specialized departments and capabilities.In fact, the Fourth Hospital was able to respond to patients with DIC many times in a row, and successfully stabilized their vital signs, in fact, thanks to these professional departments that have only recently begun to be gradually subdivided.Only they can accurately respond to the severe fluctuation of the patient's vital signs, and precisely adjust anticoagulant drugs such as low molecular weight heparin, so as to save the patient's life with as few side effects as possible.

But even with the full assistance of the two departments, Hou Huiying only managed to save her life—she was still far, far away from being completely safe.

The biggest trouble was the damage to her liver.

Yersinia pestis can damage every organ in the body, and the liver, as the largest detoxification organ in the human body, is undoubtedly one of the most severely damaged organs in this storm.Whether it's the damaged and dead cells, the toxic substances secreted by bacteria, or even the various drugs that the Fourth Hospital used in large quantities to treat her disease.Many factors are harming Hou Huiying's liver.

What really broke her liver was the numerous microthrombosis caused by DIC.

A large number of microthrombosis appeared in Hou Huiying's liver and lungs, and also caused multiple subcutaneous hemorrhages on Hou Huiying's skin.Large chunks of purple subcutaneous hemorrhage marks make people feel chilling.

The doctors in the emergency room alone could no longer stabilize Hou Huiying's vital signs. After several consultations with the departments of hematology and transfusion medicine, the departments of hematology and transfusion medicine decided to send doctors to stay in the clean room of the emergency room for treatment.Hou Huiying was given low-molecular-weight heparin, hemostasis and fibrinogen supplementation.After two days of treatment, Hou Huiying's blood coagulation function and hematuria improved slightly, but her liver function still showed no signs of improvement—her total bilirubin was hovering around 400.

"Starting today, your mother will be treated with an artificial liver." Sun Lien, wearing a P4 protective suit, said to Tang Wen who was standing beside him, "How do you feel today?"

Tang Wen was silent for a while and then sighed, "I'm still alive, that's enough." He looked worriedly at his unconscious mother and the bruises on her arms, "Will an artificial liver work?"

"As long as the machine works normally, it will be useful." Sun Lien tried to cheer up this "big boy" who was about his own age, "The artificial liver will replace your mother's liver to a certain extent, so that the condition in her body will gradually return to normal. A relatively normal level…”

"And then?" Tang Wen sat down beside his mother's bed, and sighed, "According to what you said, her liver damage has reached the point where she can't recover by herself, right? Will she be relying on artificial liver all the time? "He looked at the artificial liver that had been brought in after all kinds of hardships, and the circles of his eyes suddenly turned red.

Sun Lien put down his work and patted Tang Wen's shoulder lightly, "I fully understand how much pressure you are under now, but I must ask you to be strong." He pointed to the two beds beside him, "Your parents are now They are not completely out of danger yet, and both of them are in a coma. There are many decisions that need you to make for them-I know you are almost overwhelmed, but I can only say this, you have to carry on .”

"You're really not good at comforting people." Tang Wen pretended to rub his stomach, "My stomach hurts from what you've said."

Although he still spoke nasally, at least he seemed to be cheered up.

"Your level of joking is not too high." Sun Lien came over and pressed Tang Wen's stomach, pretending to be an examination, "Don't lie to the doctor about your symptoms! You still want to suffer hundreds more check?"

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"Dr. Sun, I have something to ask you." The doctors in the expert group who specialize in critical care medicine and the doctors of critical care medicine from the Fourth Hospital worked together to connect the artificial liver to Hou Huiying.On the side, Sun Lien was marking Hou Huiying's current vital signs in the notebook.After Sun Lien put down his pen, Tang Wen suddenly called to stop Sun Lien, "My mother's current situation, if the liver's condition doesn't improve, should I consider liver transplantation?"

Sun Li'en nodded, "This is the worst case, but liver transplantation is indeed the last and most thorough method."

"I just checked." Tang Wen showed Sun Li'en the mobile phone in his hand, "relatives can donate livers."

Sun Li'en had already guessed what Tang Wen meant, he shook his head towards Tang Wen, "Unfortunately, you can't."

"Why?" Tang Wen became impatient, "Why can't I? Why?"

"Have you forgotten why you were sent to the hospital?" Sun Lien pointed to the protective clothing on his body, "Plague, you are infected with the plague. Infected patients are absolutely not allowed to donate their organs."

People who are infected are absolutely not allowed to accept or make organ donations.The reason is also very simple and straightforward - in order to ensure the survival of the transplanted organ, the patient who received the organ needs to take immunosuppressive drugs for a long time to prevent rejection.Even the living donor liver transplantation between mother and child is the same.

The Yersinia pestis in Tang Wen's body has not been completely eliminated, and the same is true for Hou Huiying.Transplantation under such conditions would either waste the liver donated by Tang Wen, or Hou Huiying would die of the plague due to immune system suppression.This kind of operation, which is no different from murder, would not be performed by any sane doctor.

Looking at Tang Wen who suddenly became fatigued, Sun Lien sighed and persuaded, "Don't think so much now, the real thing is to cure yourself as soon as possible - if you want to donate your liver, at least you must ensure that the liver you donate Won't make your mother sick again?"

Sun Li'en also guessed that this was probably the only way Tang Wen could think of under pressure to save his mother's life.Regardless of whether this method is really useful or not, at least this idea itself represents Tang Wen's determination.This point is also very important for doctors-you must know that not everyone has the courage to actively recommend that the doctor cut open his stomach and dig out half of his liver from it to donate to his mother.

This has nothing to do with filial piety or not, and to some extent it has nothing to do with courage.People are always in fear and fear.For these worries and fears, some people choose to confront them directly, while others choose to avoid talking about them.This is not shameful, it is just the differences shown by different individuals in the human race.It's like different people react differently to atropine.

There is no shame in refusing, but it is heroic to offer.Sun Li'en patted Tang Wen's shoulder and said seriously, "The matter has not reached this point yet, so don't worry."

"Is it possible..." Tang Wen suddenly put forward a new hypothesis, "Infuse my mother's blood into my body, and then use my liver to filter waste for her? Live livers are always better than man-made ones." Is the liver useful?"

Sun Li'en almost spit on the mask of the P4 protective clothing, "Where did you come up with such a bad idea?"

"Bad idea?" Tang Wen looked puzzled and angry, "What's wrong with this idea? Both my mother and I have type O blood..."

"First of all, you and your mother's blood must not be transfused directly to each other. Especially you can't transfuse your mother's blood." Sun Lien sighed, and began to popularize the relevant blood transfusion knowledge with Tang Wenke. "Your blood contains lymphocytes. These lymphocytes in your body will not be recognized as antigens by your mother's immune system. So they will live in your mother's body, and then start to multiply in large numbers, and finally turn against the guest , to attack your mother’s digestive system and hematopoietic system.” Sun Lien made an analogy, “This process is a bit of a magpie’s nest. But the result is much more dangerous. Blood transfusions between relatives can easily lead to graft-versus-host disease (GVHD). Once this disease is triggered, the mortality rate is about [-]%—this is much worse than liver failure or even the plague.”

"But I often act like this in TV dramas..." Tang Wen still wanted to argue, "It's just a blood transfusion. Isn't there such a risk when other people's blood is transfused into the human body?"

Sun Li'en sighed with a bitter face, "There is nothing I can do about acting like this in TV dramas. If they acted wrong, they would be scolded by us doctors. But if we follow them, we will die. " He continued, "Graft-versus-host disease is one of the most serious blood transfusion complications. Blood transfusions between people who are not related may also occur, but the probability is very low, only about 0.1%. For human beings, the risk of blood transfusion will suddenly increase by ten or twenty times. Even if we have to transfuse blood between immediate family members for some special reasons, we must first irradiate the blood with a radiation source to kill the lymphocytes inside. Blood transfusion."

Sun Li'en looked at Tang Wen's face and said seriously, "We still have many other methods that we haven't tried, so don't be too anxious, the matter hasn't reached this point yet."

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"The matter has not reached this point yet." In the conference room, Wu Youqian, who heard Sun Lien's report, also made the same judgment, "Artificial liver replacement therapy is the best treatment at present. As for the willingness of the family members to donate their livers—— Good thing, but not there yet."

"I think so too." Sun Li'en nodded, and after getting out of the P4 protective clothing, he felt a lot lighter all over his body. "But after all, I was trapped in the clean room for three consecutive days, my parents fell into a coma, and my mother's condition was especially serious... I think we should give Tang Wen some psychological intervention. If this continues, he may not be able to bear it."

"This child is not very old." Wu Youqian nodded, "We should think about this issue." He nodded the table in front of him, "Put Hou Huiying on the liver transplant list, we can grab some time That’s one thing—if her plague has not been completely eradicated when a liver source is available, the transplant will be given up.”

(End of this chapter)