I can see the status bar

Chapter 1019 D+3 day (3)

"Provide data? This is no problem." Sun Lien immediately agreed.All he wants is a license to use tocilizumab for patients, and as long as there is a license, other things can be relied on.Anyway, he didn't plan to post any more articles with this treatment, so there was no need to keep the data confidential.Rather, Sun Lien even hopes that this treatment data can be made public every day-so that other doctors can realize the importance of precise control of the immune system earlier.

Regulating the immune system of patients with novel coronavirus is a much more rigorous and complex "art" than ordinary immune regulation.In the absence of effective antiviral drugs, recovery must rely on the body's own immune system response.Only when the immune system recognizes the virus and produces enough neutralizing antibodies can it be possible to remove these viruses from the human body.

Only when the immune system is strong enough can it produce enough neutralizing antibodies before the virus causes irreparable damage to the human body.But a strong immune system will keep killing lung epithelial cells in order to control the speed of virus infection of cells.

The overall suppression of the immune system through hormones may cause the patient's immune system to slowly produce neutralizing antibodies.The result of this is that before enough antibodies are produced, the human body will be infected by a large area of ​​lung epithelial cells and other cells containing ACE2 receptors, resulting in severe organ damage and even death.

And what if the immune system responded just right?Virus infection starts from the lower respiratory tract, from the edge of the lungs.As a viral infection, its nature is closer to interstitial pneumonia.However, the carbon dioxide retention in such pneumonia infection is relatively mild, and there is no warning of increased carbon dioxide concentration. It is difficult for peripheral chemoreceptors and central chemoreceptors to respond to this, and spontaneously enhance breathing.

The worst result...is the "silent hypoxemia" discovered by Director Huang Wenhui in clinical practice.

Life support is necessary to keep symptomatic COVID-[-] patients alive.Oxygen inhalation in the early stage, regulation of the immune system response in the middle stage, and maintenance of vital signs in the later stage.Only by implementing thousands of strategies and accurately identifying and treating each patient can it be possible to improve the overall cure rate and allow more patients to survive.

The "use of tocilizumab" proposed by Sun Lien is a new attempt to regulate the immune system response in the medium term.He hopes that by using this drug, it can weaken the immune system's killing effect on cells, block the cell storm, and maintain the speed of antibody production.

But whether it has any effect, whether it can meet the expectations of myself and Dr. Pascal... It's hard to say.

"I have another suggestion." After being silent for a while, Sun Lien said to the staff of the Health and Medical Commission, "I suggest that we should start the autopsy of the dead patients as soon as possible."

The proposal sparked a moment of silence at the scene.

"We have suggested this kind of thing a long time ago." The leader of the Shanghai Stock Exchange sighed, "However, due to the sudden epidemic, most of the patients who passed away were elderly. The family members should be mobilized to agree to the autopsy during the Chinese New Year... It's too difficult."

"More importantly, mobilizing the autopsy now may make some family members have some bad ideas." Shonan's team leader added, "Most of them have violent mood swings, and the sudden closure of the city made many people feel that they Abandoned, mobilize them to agree to do an autopsy, I'm afraid people will think that we deliberately put people to death... Director Sun, you haven't been online much recently, have you?"

"No." Sun Lien was a little surprised by this question, "Did something happen on the Internet?"

"All the demons and ghosts are out." The Shonan team leader shook his head and said, "There are a few young kids in our team who like to surf the Internet. Can't eat it."

Sun Li'en doesn't know much about public opinion.However, when there is obviously a problem with this wind direction, it is true that every move must be more careful.

"I don't understand the matter of public opinion." Sun Li'en shook his head, and decided to follow the previous working principles - leaving professional matters to professionals. "Just ask the relevant departments to pay attention to this kind of thing. We still have to make suggestions. We must start anatomical and pathological examination of the deceased's body as soon as possible. This is very important to indicate the direction of future research and treatment."

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There are some things that should be done immediately.But in order to achieve better results, it is necessary to adjust the implementation time node.This kind of counter-intuitive thing exists in many fields. "In order for the human immune system to better generate neutralizing antibodies to fight against viruses, the immune system needs to be suppressed" is a specific example of this kind of thing.

In the process of the operation of this society, there are many similar situations.But... the difficulty of convincing millions of people is far more difficult than convincing the family members of two or three patients.The resistance, risks and challenges faced by relevant departments when implementing relevant decisions are by no means what Sun Lien can understand.

A city with a population of more than 1000 million was completely blocked with one order.It is conceivable how much political courage and decisiveness this requires, and how many difficulties and challenges it will face.

"We will coordinate as soon as possible for the problems that the leaders have responded to." Before the meeting ended, the staff of the Yunhe City Health and Health Commission tried their best to put a smile on their tired faces, "You also have our contact numbers. If necessary, you can directly contact the staff of the Health and Medical Commission who have been connected to you - you can also call me directly."

"It's not that the protective clothing used in the chemical industry is unusable, at least the protective clothing we can provide to you now still meets the relevant protection standards." The comrade in charge of the Health and Medical Commission finally said regretfully, "Donations from all over the country are being donated to Yunhe is assembled, and the allocation of materials will take some time to resolve. Before the shortage is alleviated, please be patient for a while."

The industrial protective clothing coordinated by the Health and Medical Commission is actually not much different from medical protective clothing.However, compared with medical protective clothing, there is one less self-adhesive sticker used to prevent liquid splashes from penetrating into the zipper.

Personally, Sun Lien is more optimistic - if there is no self-adhesive sticker, then stick it with tape.Anyway, there is no shoe cover, so the doctors carried it with garbage bags.

With the help of the status bar, the role that Sun Lien can play in preventing the hospital feeling cannot be underestimated.Through the application of the status bar in the past few years, Sun Lien summed up a set of methods for using the status bar to judge personal protection.If the level of protective clothing he wears is high enough, then the reminder on the status bar after entering the red zone is usually the banner type—concentrated on the top and right side of the line of sight.

If the protection level is not enough, or he took off the mask by himself.Then the high-risk warnings on the status bar will be thrown on his face overwhelmingly, even to the point where it will affect his sight.Unless Sun Lien actively closes the status bar, the warning will always appear.

Whether the combination of industrial protective clothing and medical garbage bags can stop the new coronavirus is not easy to judge based on data alone, but Sun Lien will know if he puts on protective clothing and goes around the red zone.

Almost all medical protective clothing will be used up by tomorrow.Sun Li'en decided that tonight, he would put on his industrial protective clothing and go in to have a look.

(End of this chapter)