I just want to be a quiet scholar

Chapter 640 Yes, No
After full consideration, Shen Qi respected the decision of the ethics committee, and all patients with type R anemia would be selected as subjects for the phase I clinical trial of triazoctenes.

The next step is to recruit R-type anemia patients as test subjects. Professor Qu has some resources in his hands. He quickly recruited a group of R-type anemia patients, and then signed another round of informed consent and reviewed by the ethics committee.

Ouye basically understands the general situation of Shen Qi's scientific research projects.

That night, before going to sleep, Ouye said to Shen Qi on the bed: "Surprisingly, for the phase I clinical trial of triazoctenes, let me also be included in the group."

Shen Qi objected: "I'll give you this medicine after it's successfully marketed."

"It will be several years later?" Ouye showed her firm determination to seize the day and see death as home. She said, "I am also a patient, and I want to participate in clinical trials."

"Triazaoctenene is a new drug, and it has risks." Shen Qi didn't need to explain too much, he thought that Ouye should also know the risks of the new drug.

Drug clinical trials, it is an experiment, and the new drugs selected are experimental products.

Since it is a test product, it is more or less risky.

Ouye still insisted on her idea: "Qi, just use me as an experiment. I am a qualified sample with 20 years of experience in taking medicine, and I am especially suitable for tolerance testing."

"No! I can't use my wife for human experiments!"

"not bad."

"do not want!"

"What do you want?"

"Little Yezi, don't force me to use domestic violence."

"come on."

"I... what?"

"Yeah... So Qi, do you agree?"

"Little Yezi, I understand your thoughts, you want to get cured quickly. But let me explain to you the purpose of the Phase I clinical trial..."

Phase I clinical trials are the initial stage of human trials of new drugs. From animals to humans, due to the different species, although the results of animal toxicity experiments have important reference value, the reactions of drugs in humans are usually different from those in animals.

Phase I clinical trials mainly include human tolerance tests and human pharmacokinetic tests.

The tolerance test specifically includes observing adverse reactions, the relationship between dose and adverse reaction, the relationship between abnormal laboratory indicators and dose, etc., so as to obtain the dose range that the human body can tolerate the new drug, and provide a basis for subsequent pharmacokinetic tests and Phase II clinical trials provide important reference data.

Ouye herself said that she can do tolerance tests, and she has a certain understanding of clinical trials.

After the tolerance test is completed, the pharmacokinetic/efficacy test will be carried out in the phase I clinical trial.

Ouye's idea is actually very simple, what if I am cured in the phase I clinical trial?

Although Phase I clinical trials are risky, patients with the target disease are the first to be exposed to new drugs. It can be understood that they are the first people in the world to receive this new drug treatment.

It really has to wait until the new drug has passed the second, third, and fourth phases of clinical trials, and all risks have been ruled out, which can range from a few years to more than ten years.

Ouye didn't want to wait anymore, she was worried that if she just waited and waited, she might have to wait until the day of menopause.

So Ouye resolutely launched a big move. She was extremely eager to participate in clinical trials and get in touch with new drugs as soon as possible.There are risks, but there is also hope.

Shen Qi didn't sleep well all night, he thought a lot, a lot.

After dawn, Shen Qi approved his wife's application: "Send you into the group for clinical trials."

Throughout the history of medicine and drugs, there are great scientists or lunatics who used their own bodies to conduct human experiments.

But no one has ever done human experiments on their spouses.

Shen Qi is No.1.

The trust and mutual support between husband and wife are all in the experiment and in the medicine.

Is the wife dead or alive, recovering or deteriorating?

To grow old together, or to be alone and widower?

It depends on Shen Qi's scientific research level.

"Chemistry and biology, we must upgrade as soon as possible..." Shen Qi's chemistry is level 13, and biology is level 12.Biochemistry is master level.

But Shen Qi is still a little uneasy, in case something goes wrong in his wife's clinical trial, of course, the higher the level of biochemistry, the greater the possibility of solving the problem, the higher the efficiency, and the stronger the accuracy.

Xueba points are enough.

Chemistry level 13 to 14, biology level 12 to 13, all need to complete the task.

"Let's finish the chemistry task first..." Shen Qi's chemistry promotion to level 14 was actually more than half completed, and he missed the goal.

Yanda University of Mathematics.

Ouye is making work handover arrangements.

In principle, the test subjects of clinical trials need to be admitted to the hospital, which is convenient for clinical trial medical staff to carry out their work, and can better guarantee the clinical trial results.

Ouye will be admitted to the observation ward of Yanda People's Hospital, the shortest period is three months, five months, and the longest period is one year.

She first asked for sick leave with the leaders of several hospitals, and she took six months.

"Xiao Ou, are you going to be hospitalized? Your health is critical, and I agree with your sick leave application. Come on, I hope you get better soon." The dean of the number hospital had no objection, and he approved Ouye's leave request.

In terms of work, there is actually nothing to hand over. Ouye is doing an independent project at his own expense, and he didn't even write a project approval report.

"Sister Ye Zi, are you going to be hospitalized? When are you coming back?" Zhao Tian, ​​Xiao Yun, and Zeng Han, three mathematics students, asked with great concern.

"I took a leave of absence for half a year. I hope I can come back within half a year. You three, don't stop working on the BSD conjecture." What Ouye cares most about is the BSD conjecture. This project has been done for a while and has achieved certain results. Research experience.

Although concerned about the BSD conjecture, Ouye also figured it out. The body is the capital of revolution, and health is the guarantee of scientific research.

The three students were full of worries. First of all, they were worried about Sister Ye Zi's physical condition, and secondly, they felt sorry for the BSD conjecture.

Sister Yezi is not here, BSD guesses that it can't go on.

Doing mathematics projects is a continuous project. Usually, if you stop for half a year, it may be cold.

If I want to continue after half a year, firstly, the discontinuity in thinking will lead to low efficiency, and secondly, the morale of the team will also be affected.

However, Ouye doesn't think so: "I'm hospitalized, not in prison. We can contact you at any time. What you three have to do is to calculate the group theory model. As for how to calculate, I have already told you. I need to do it again. Tell me again?"

Zhao Tian said: "The three of us have mastered the calculation principles and methods of the group theory model taught by Sister Ye Zi. In fact, we have already calculated the preliminary results of the group structure yesterday, and we are about to review it for Sister Ye Zi, but Sister Ye Zi You tell us now that you will be hospitalized for half a year...Of course, Miss Ye Zi's health will always come first!"

"Oh, is that right, figured it out? Send the editable version of the file to my mailbox, and I will read it. Thank you for your hard work, I'm leaving." Ouye waved his hand to say goodbye to the three students, and then stepped on On a hospital trip.

(End of this chapter)