Xueba's life simulator

Chapter 226 Cloning Experiment Team
"The technology of artificial organs is more advanced than the technology of artificial meat. If you can really achieve results in artificial organs, you can indeed take the technology of artificial meat one step further.

However, let alone artificial organ technology, it is artificial meat technology, although as early as four years ago, someone had already launched the world's first piece of artificial meat grown in a laboratory.

But I remember foodies who tasted the piece of faux meat commented that the lack of fat in the meat was obvious.

The reason why it tastes so different from natural meat may be because it has no muscle cells, fibroblasts, fat cells, and blood vessel cells.

However, if these cells are to be cultured together, complex culture systems and metabolic conditions are required, so that it is possible to cultivate meat-like muscle tissue.

Well, let’s not talk about the issue of artificial organs. Since you mentioned artificial meat, how are you going to solve the problems I just mentioned? "

After listening to Zhou Ming, Su Xueming asked him a question.

If we can't even solve this problem of artificial meat, let alone create human organs that can be used for organ transplantation.

"If you just want to make artificial meat have the delicious taste of natural meat, in my opinion, it doesn't need to be too complicated. We just need to find an edible 'scaffold' material that allows muscle cells to attach and grow in 3D. environment to grow."

Zhou Ming explained to Su Xueming.

After listening to Zhou Ming's explanation, Su Xueming is worthy of being an old professor, and he immediately understood the key point of Zhou Ming's words.

"So, the important thing here is to find an efficient way to mass-produce these scaffolds, right?" Su Xueming said to Zhou Ming.

"Well, that's right." Zhou Ming nodded and continued, "Whether it is to find this kind of 'stent' material or to mass-produce these scaffolds, we have a way. And we can also adjust the type of these scaffold fibers, Experiment with more complex textures, flavors and nutritional profiles.

However, the methods we are going to use are not these. "

"Oh?" Hearing Zhou Ming's last sentence, Su Xueming was full of curiosity, and he asked Zhou Ming with some uncertainty, "The method you said to use is not these, it refers to not using the 'bracket' material ?”

The reason why Su Xueming is curious is because the current research on cloning organs requires scaffolding.

In the process of cloning organs, if you want to make cells grow three-dimensionally and form the structure and shape of the organ, you need an organ scaffold. This is how current organ cloning technology has developed.

However, although simple organ scaffolds can indeed be prepared with the current development of biomaterials, it is still very far away from being usable.

But now, Zhou Ming said that he didn't need this method.

The meaning of Zhou Ming's words was obviously that he could get rid of the existing 'scaffold' research system for organ cloning and create a new technology for organ cloning.

If this is the case, this is definitely a major breakthrough, which is why Su Xueming is a little uncertain. He wonders if he has misunderstood what Zhou Ming said.

"That's right, the method we are going to use is environment-simulating cloning, that is, creating an environment similar to the growth of organs in the human body, and then using this environment for the cultivation of cloned organs."

Zhou Ming nodded and explained to Su Mingjie.

"Environment-inspired cloning? Is it a technology similar to bionic manufacturing?"

I heard Zhou Ming pull out another imitation environment clone. If Zhou Ming hadn't said this, Su Mingjie would have kicked Zhou Ming out as a big liar who was fooling around. How could he still be sitting here, continuing to talk to Zhou Ming? Explore what he means by faux-environmental cloning.

However, after saying this, Su Xueming himself felt that the anti-environmental cloning mentioned by Zhou Ming and the current bionic manufacturing were completely two different things.

The so-called bionic production refers to the manufacturing system and manufacturing process that imitates the organizational structure and operation mode of organisms. It responds quickly to market demand and protects nature by simulating the functions of biological organs such as self-organization, self-healing, self-growth and self-evolution. environment.

The current manufacturing system is also increasingly tending to be large-scale, complex, dynamic and highly nonlinear.

Therefore, people select the content that is rich in inspiration for engineering technology from the basic research results of life sciences, combine these research results with manufacturing science, establish new manufacturing models and study new bionic processing methods.

"These two are different, one of them is industrial manufacturing, focusing on industry, the other is cloning, focusing on biology.

The imitation environment cloning is mainly to create a cell differentiation site for the cloned organ, so as to prevent it from growing into a puddle of meat, but its differentiation will be in the direction we want.

The difficulty of this method at the beginning is that its growth cycle is too slow, even if human intervention is performed, it will only grow two or three times faster than normal human organs. "

Zhou Ming explained to Su Xueming.

Su Xueming really became more and more interested the more he listened. The meaning of Zhou Ming's words was obviously to artificially create a person's internal biological environment.

However, if the organ cloning is really carried out according to the growth method of the organs in the ordinary human body, then this speed will be too slow.

If a young man in his 20s wants to undergo organ transplantation, with Zhou Ming's organ cloning technology, you can clone an organ with the same gene, but the speed is too slow.

Even if it grows two or three times faster than normal human organs, if you really want to cultivate it into the organs of a 20-year-old boy, it will take several years.

People are in a hurry to get their organs transplanted, and then the doctor said to ask him to wait another seven or eight years. Isn't this a joke?
And another point is that some diseases are not an acquired problem, but a congenital genetic problem. Even if you change the organ, if you use the patient's original gene for cloning and culture, won't the cultivated organ still have a problem?

The more interested you are, the deeper you think, and the deeper you think, the more problems you discover.

And Su Xueming also told Zhou Ming all these questions in his mind.

Zhou Ming was also very happy to see Su Xueming writing "I'm very interested" all over his face and talking to himself about the questions he was thinking of now.

Because this shows that Su Xueming is very interested in the research he mentioned, and being interested means that it is easier to pull him into his team.

"Professor Su, I have solutions to these problems, but I can't just tell you the solutions to these problems so casually.

This involves confidential technology. If you can join my newly established experimental group, I can slowly tell you the solution to these problems. "

Zhou Ming said mysteriously, with a smile still on his face.

Facing Zhou Ming's words, Su Xueming had a wonderful feeling that Grandma Wolf made up excuses to abduct Little Red Riding Hood.

However, in the end Su Xueming agreed to Zhou Ming's invitation, and he said to Zhou Ming: "If you can really solve these problems, then of course I am very happy to join your new experimental group.

But if I join in and find that you have no solution to these problems, then I won't stay with you anymore. "

"Don't worry about this, Director Su. Then you won't have the idea of ​​leaving." Zhou Ming said with a cheerful smile.

Seeing that Zhou Ming was so confident, Su Xueming said to him again: "Are you going to start cloning directly from human somatic cells, and start to start with animals? If you start with animals first, then you should start with non-human primates as well." At first, I can recommend someone to you."

Zhou Ming's laboratory has just been established, and it is the time when there is a shortage of people, so after Su Xueming told him so, Zhou Ming also showed a more interested expression, and asked Su Xueming: "Who is it? Can you briefly introduce it? ?"

"This is also what I met in the Huaguo Academy of Sciences Center for Excellence in Brain Science. His name is Ren Le, and he is the director of the non-human primate research (Gusu) platform of the Neuroscience Institute of the Huaguo Academy of Sciences. Member of Center of Excellence for Innovation in Science and Intelligent Technology.

He was previously engaged in research on experimental animals and transgenic mice, reproductive physiology of non-human primates and the construction of transgenic monkeys.

Although he graduated from Zhelimu College of Animal Husbandry in Inner Mongolia with a bachelor's degree, he also completed his master's career at Guangling University, and his doctorate in pharmacology at the Modu Medical Research Institute.

However, he is still very hard working, but I don't know if your new laboratory will accept it. "

In addition to being the director of the Institute of Neuroscience, Huaguo Academy of Sciences, Modu Life Sciences Institute, Su Xueming also serves as the director of the Brain Science Excellence Innovation Center of the Huaguo Academy of Sciences, so he knows the same as the Brain Science and Intelligent Technology Excellence Innovation Center of the Huaguo Academy of Sciences The members' enjoyment is also normal.

Moreover, from the fact that he can name Ren Le's undergraduate, master's and doctoral schools, it can also be seen that he usually pays close attention to Ren Le.

"Ren Le?" After listening to Su Xueming's general introduction to this person, Zhou Ming held his chin with one hand and began to think in his mind to see if he had such a number one person in his mind.

After thinking for a while, Zhou Ming did not find Ren Le's name in his brain, so he said to Su Xueming: "Since it was recommended by Director Su, then I can take a look.

However, since he is now the director of the non-human primate research (Gusu) platform of the Institute of Neuroscience, Huaguo Academy of Sciences, and you also said that he works very hard, if he joins my experimental group, I am worried He doesn't have the energy to take care of both ends. "

"It depends on what he thinks. If he can pass the review, I think he will still agree to give up his job at the research institute.

After all, no matter what angle you look at, if you have the opportunity to go to your side, you must have a better future than staying in a research institute. "

Su Xueming said.

"How to say?" Zhou Ming asked, he was also a little curious about what kind of existence his laboratory was in the eyes of other people.

Now that Su Xueming has said so, Zhou Ming can just take this opportunity to know what his laboratory looks like in the eyes of others.

"First of all, in terms of attention, whether it is the academic circle or the higher authorities, the attention to your laboratory is quite high. After all, the results produced by your laboratories every time are not comparable to ordinary people.

With the attention and achievements, even if you work there for two years for nothing, after you come out, you can find a job in other places, and your worth will be very different from before you go to your place.

If you go to the United States, the treatment you can enjoy will definitely be better. After all, the United States also wants to know the situation in your laboratory very much.

Although no one has resigned from your laboratory so far, I think even if there is, if you really want to go to the United States, I am afraid that the above will not approve it.

Besides, in terms of remuneration, the remuneration of your laboratory should not be comparable to that of many institutions at home and abroad.

You said, like this kind of treatment, you need to be treated well, you want to be famous, you can do experiments with peace of mind, and the results are produced like a hen laying eggs. Who wouldn't want to go?Especially those who are not particularly famous, I want to go even more.

In other words, those who want to climb to high positions through scientific research may not want to go to your place, but that is not necessarily the case. After all, staying there for a few years and then coming out is considered gold-plated, and the road to promotion may be more convenient in the future. Maybe. "

Su Xueming said to Zhou Ming.

I have to say, no wonder there was a common saying in ancient times, "Thousands of wears, ten thousand wears, flattering does not wear", and it has been applied until now. Now Zhou Ming listens to what Su Xueming said, and he is really very useful in his heart.

"Director Su, don't worry, as long as you join in, you won't regret it." Zhou Ming said to Su Xueming.

After Zhou Ming left Shanghai, Su Xueming's actions were also very fast, and he quickly contacted Ren Le.

As for Zhou Ming, after returning to Luzhou, through more detailed information, he had a clearer understanding of the Ren Le recommended by Su Xueming.

His general situation is similar to what Su Xueming said, and his diligence is even worse than what Su Xueming said.
According to Zhou Ming's understanding, Ren Le is currently conducting three experiments, one is related to gene knockout in mice and monkeys, one is related to target integration, and the other is related to rat hippocampus The experiment can be said to be very liver.

Last year, Ren Le also published two papers.

Judging from the schools where Ren Le attended his undergraduate and master’s degrees, he is not a very talented person, but such a person can now serve as the director of the non-human primate research (Gusu) platform of the Institute of Neuroscience, Huaguo Academy of Sciences , became a member of the Brain Science and Intelligent Technology Excellence Innovation Center of the Huaguo Academy of Sciences, and was so valued by an academician like Su Xueming precisely because of his diligence.

Zhou Ming likes such people, because they can complete the experimental tasks given by Zhou Ming more quickly, and the speed of producing results will be higher than that of ordinary people.

On the third day after Zhou Ming returned to Luzhou, Ren Le contacted Zhou Ming, and Zhou Ming also conducted an assessment through the Internet. In the end, this person also successfully passed Zhou Ming's assessment.

And with the help of Zhang Mingjie and Su Xueming, the two academicians, Zhou Ming's newly established experimental team was almost recruited soon.

After getting them to sign the contract, Zhou Ming handed over the experimental plan for the first phase to Su Xueming.

"This... this... this plan is too detailed?"

After seeing the research plan given to him by Zhou Ming, Su Xueming's eyes widened and he said to him in disbelief.

Zhou Ming's current experimental team arrangement is generally that a team arranges an academician or a scholar with outstanding achievements in this field as the general manager.

As for the specific research plan, Zhou Ming will hand it over to the chief person in charge. After that, the chief person in charge and Zhou Ming will discuss and assign different experiments.

"No wonder your experimental groups were able to produce results so quickly. There are no bottlenecks. If we can all follow your plan, then our side should be the same as your previous experimental groups."

Su Xueming continued to speak, the shock on his face did not dissipate for a long time.

"Haha, the specific experiments that will follow will be left to Director Su. I estimate that the preliminary results should be completed before this summer vacation. I will hand over the subsequent experimental plans to Director Su at that time."

Zhou Ming smiled and said that Su Xueming's performance was within his expectation.

(End of this chapter)